What is the treatment of anti -angiogenesis?
Treatment of anti-English is a promising new form of cancer therapy. Specially designed drugs inhibit the growth of new blood vessels inside and lead to cancer tumors. Without a permanent blood supply, tumors will cease to grow, and many cancer cells will eventually die. For the treatment of colorectal, renal, renal, pancreatic and pulmonary cancer, several different types of anti -angiogenesis drugs take place and clinical trial is underway to determine the effectiveness of drugs against other types of malignancies. Many experts believe that the combination of treatment of anti -angiogenesis with other established treatment methods such as chemotherapy and radiation provides a very promising view of the battle with cancer.
Most anti-English drugs are designed to stop the activity of a protein called vascular endothelial growth factor (VEGF), which controls the production and maintenance of cells of blood vessels. Many healthy cells in the body have a small amount to help wound healing and maintain existing blood vessels strong. Some types rHowever, acoric cells produce excessively large amounts of VEGF that cause the rapid development of new blood vessels to feed the host tumor. VEGF inhibitors effectively prevent VEGF replication to provide blood vessel instructions.
The most popular anti -angiogenesis medicine, bevacizumab, works by looking for vegf and binding directly to protein. After creating a custody, the Vegf cannot communicate with the receptor on the cells of the blood vessels. Another cure, cetuximab, is achieved by blocking the receptor site instead of a combination with a vegf protein. The ongoing research of biochemical companies, pharmaceutical companies and hospitals is underway to develop new ways of disruption of VEGF and prevent tumor growth.
The risks of side effects with drugs against angiogenesis are low, ezváště compared to other cancer treatments. Unlike chemotherapeutic substances that damage the immune system, they have anti -angiogenesis drugsVery limited negative effects outside tumors. During treatment, the patient may experience slow or ineffective wound healing. Bleeding into stomach or intestines is possible, especially in people who already have large digestive disorders or bleeding complications. Some patients also experience a sudden increase in blood pressure, which may become serious problems in rare circumstances.
Clinical studies and real treatment suggest that medicines against angiogenesis work best when used in combination with other therapies of cancer fighting. Once the blood supply of the tumor is significantly exhausted, chemotherapy and radiation can be more efficient when reducing it. With continuing research, professionals hope to integrate anti -angiogenesis into a standard therapeutic regime for many different cancer.