What Is Arecoline?

Arecoline is used medically to treat glaucoma and can paralyze roundworms, so it is also used as a pinworm repellent and has better effect with pumpkin kernels. It is clinically used to treat postpartum uterine bleeding, poor uterine regeneration, and excessive menstruation.

Arecoline

There are pseudocholine effects. And has a role like nicotine. It is used medically to treat glaucoma and can paralyze roundworms, so it is also used as a roundworm repellent and has better effect with pumpkin kernels. Can directly affect uterine smooth muscle. Large doses can cause uterine tonic contraction, and can achieve hemostasis. It is clinically used to treat postpartum uterine bleeding, poor uterine regeneration, and excessive menstruation.

In addition to betel nut extraction, it can also be artificially synthesized.

The invention provides a method for preparing arecoline or its analogs. in

Numbering	Toxicity type	testing method	Test object	Dosage used	Toxic effect
1	Acute toxicity	Parenteral	Rat	270 mg / kg	Detailed effects are not reported other than lethal dose
2	Acute toxicity	oral	Mouse	600 mg / kg	Detailed effects are not reported other than lethal dose
3	Acute toxicity	Subcutaneous injection	Mouse	65 mg / kg	Detailed effects are not reported other than lethal dose
4	Acute toxicity	Intravenous injection	Mouse	18 mg / kg	Detailed effects are not reported other than lethal dose
5	Acute toxicity	Parenteral	frog	160 mg / kg	Detailed effects are not reported other than lethal dose
6	Chronic toxicity	Subcutaneous injection	Mouse	210 mg / kg / 3W-I	1. Immune system toxicity-reduced cellular immune response

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