What is cellular immunotherapy?
cellular immunotherapy is a method of treatment of cancer, which generally works by running the patient's immune system against tumor cells. This can be achieved by extraction of cells and harvesting of culture that returns to the body. Substances can also be injected to start the process. The aim is to get the immune system to recognize tumor cells and overcome the effects of substances called cytokines that can suppress the immune response to cancer. Various clinical trials tested different methods of cellular immunotherapy during the first decade of the 21st century. In another strategy, genes that code immune responses can be inserted into tumor cells. Cytokines are sometimes used to stimulate the immune system around the affected area; In use locally, side effects usually avoid. Another type of immunotherapy involves the use of dendritic cells, which usually acts as messengers to other types of immune cells. These can be filled with compounds that target cancer cells, and sometimes used to create a type of vaccine.
Some treatment of cellular immunotherapy use immune ingredients called T cells. This treatment often focuses on the effect of many cancer to prevent the immune system to be known. Molecules that allow immune cells to target something, are often not expressed on a tumor or there are molecules that kill T cells. Sometimes immune cells from donor are transplanted into patients with leukemia and this approach can also be combined with gene therapy.
genetic engineering can also be used on cells from the patient. Once the blood sample is taken from the blood sample, molecular receptors can be added and biological material is grown outside the body. The aim is to re -implant culture to create a defense against cancer and delete it.
Some types of cellular immunotherapy have led to autoimmune conditions in humans. In treatment that serves as vaccines, some scientists think that this reaction is also possibleand. Immunotherapy is often used in patients with advanced diseases, so some of them are generally unknown. The complexity of cellular therapy often increases challenges and is usually expensive compared to other treatments. Since 2011, studies using cellular immunotherapy have been underway, usually focusing on genetic and immune science to help fight cancer, and avoiding the toxic effects of chemotherapy and other treatments.