What Is Desensitization Therapy?

Desensitization therapy is the abbreviation of specific desensitization therapy, also known as desensitization therapy. It belongs to specific immunotherapy and is a kind of allergic substances that cause allergic diseases (including allergic asthma, medical asthma, allergic dermatitis, etc.) A cure. The purpose is to reduce symptoms, shorten the onset time, and reduce the amount of medication. It is an immunotherapy specifically targeted at IgE (immunoglobulin E) -specific allergen-induced allergic diseases. The biggest disadvantage of this therapy is that the course of treatment is too long (more than 2 to 3 years), and serious adverse reactions of anaphylactic shock will occur when it is not used.

Basic Information

Chinese name

Desensitization therapy

Also known as

Desensitization treatment

aka

Specific immunotherapy

Types of

therapy

Desensitization therapy method

Desensitization therapy must first identify allergens, and then make allergens in different concentrations of preparations. Repeatedly subcutaneous injections of patients with positive allergen skin tests, from small to large doses, from low to high concentrations, gradually induce patients to resist Affected by this allergen without allergic reaction.

Indications for desensitization therapy

1. Patient symptoms are caused by a single or few allergens.

2. Patient symptoms are closely related to exposure to allergens, and exposure to allergens cannot be avoided.

3. Patients with allergic rhinitis have lower respiratory symptoms during peak allergen season.

4. Patients with seasonal hay fever who have prolonged or premature symptoms.

5. Patients with side effects caused by drug treatment.

6. Applying appropriate medications (such as inhaled glucocorticoids or oral antihistamines) does not control the symptoms well.

7. Patients who are unwilling to receive long-term medication.

Contraindications to desensitization

Absolute contraindication

Severe cardiovascular disease, immune system diseases, beta blockers, cancer, patients with uncertain allergens, and lack of compliance and severe mental disorders.

2. Relative contraindications

Children under 5 years of age and pregnant women (specific immunotherapy should not be started during pregnancy, but if treatment has been received before pregnancy and is well tolerated, there is no need to discontinue treatment), asthma is unstable or acute, and moderate to severe persistent asthma, etc. .

Adverse effects of desensitization therapy

Local urticaria, rhinitis, mild asthma, systemic reactions (such as generalized urticaria and angioedema) may occur, and anaphylactic shock may occur in severe cases.