What is manidipine?
European physicians often prescribe calcium channel blocker, manidipine, for the treatment of mild to medium high blood pressure. A comparable medicine, which is often prescribed in the United States, is nifedipine. There are three types of calcium channel blocker and each disrupts the calcium flow in a different way and in different paths of calcium. Some of these drugs affect the heart more than others. Manidipine and other drugs to block the calcium channel as a whole share similar properties and side effects.
Manidipine belongs to the class of calcium channel blockers known as dihydropyridines that inhibit calcium ion into cells. This effect causes relaxation of vascular muscles in cardiac and peripheral blood vessels, lowers blood pressure and increases blood flow. The group of drugs that include manidipine generally does not affect the power of heart contractions or changes heart rate. Further use of calcium channel blockers included treatment of angina, migraine and high blood pressure or pulmonary hypertension.
Other types of calcium channel blockers include benzothiazepines such as dilitiaz, and phenylylamins such as verapamil. Each group inhibits calcium ions, but does in different ways. Benzothiazepines and dihydropyridines act on cell surfaces, while phenylylamins are bonding on the membrane of the inner cells. In addition to lowering blood pressure, benzothiazepines and phenylylamins reduce heart rate and heart contraction strength.
patients with congestive heart failure and bradycardia or slow heart rate may be prescribed amlodipine because this calcium channel blocker has a low effect on the heart. Individuals with tachycardia or increased heart frequencies can use dilitiaz or verapamil that slow down the pulses emitted by a sinoatric node of the heart. Various Calblocators of Cium channels in a certain group can also affect different calcium pathways. Some affect the channels that OVThey live blood vessels that enter the kidneys, while others affect only the blood vessels found along the output roads. Cilnidipine calculator shows unique properties on calcium channels of nerve cells.
In general, doctors take into account the drugs before prescribing to patients, especially if the patient has more than one health condition. The side effects of manidipine include headache, flushing of the skin and dizziness. Patients may also develop skin rashes, general fatigue and swelling or swelling of the legs and ankles. Palpitations and sexual dysfunction are also not unusual side effects of calcium channel blockers. Patients should not drink grapefruit juice two hours before or four hours after removal of calcium channel blockers, as the beverage increases the level of drugs.