What is the regeneration of the optical nerve?
The optical nerve is a large cable composed of ganglion cell axons that act as a viaduct performing visual information from the retina to the brain. Several diseases such as glaucoma can damage the optical nerve and cause permanent blindness. Optical nerve regeneration restores damaged axons in the optical nerve to return the vision. Optical nerve regeneration is currently impossible in humans, but research in this area has progressed significantly in the last few years and there are several promising ideas. Building nerve grafts and manipulation of enzymes and other molecular components involved in cell growth are some of the techniques that are examined to try to create an optical nerve. However, the nerves in other parts of the body are capable of regeneration. In rats, grafting or transplantation of peripheral nerve cells for damaged optical nerve, she promoted nerve regeneration, technique that can also work in humans. Scientists work on artificial gel or polymer on the basis of grafts of peripheral nerves, toThe teré could be placed on an injured optical nerve to function as a scaffold or guide for axons to harness for regeneration.
The optical nerve regeneration puzzle is likely to be resolved, at least partially, handling the molecular pathways in the body, and several promising thoughts in this area include the gene of phosphatase and homologists (PTEN), the brain gene, and the growth factor and the growth factor to cocodulin. In humans, the gene is a piece of genetic material containing instructions on how to produce the enzyme PTEN, a key factor in stopping cell growth. We hope that if the enzyme PTEN can be blocked, axon regeneration may be possible. BDNF is a growth factor expressed by BDNFGEN and is important in the development of neurons in the optical nerve. Excessive production of this growth factor through gene therapy has led to the regeneration of nervous connections in mice.
onComodulin is a cellular growth factor that, when adding do Putting nerve cells, virtually doubled the growth of axons. When OnComodulin was placed on damaged optical nerves in rats, along with chemicals that intensify the effects of oncomodulin, the result was a significant increase in optical nerve regeneration. Once scientists are able to get axons to regenerate, they will have to make them grow to the right places and establish the correct connection to transfer the visual information to the brain, so getting axons to grow is just one part of the very complex puzzle of optical nerve regeneration.