What Is the History of Anesthetic?

Anesthesia refers to a drug or non-drug method that temporarily or reversibly loses consciousness and pain in the body or the body. It is mostly used for surgery or for treating certain diseases. "Mabosan" is the first anesthetic invented and used in the world. It was created by Hua Yi, an outstanding medical scientist in the late Eastern Han Dynasty and the Three Kingdoms Period. In the 2nd century, China has used "Mabosan" general anesthesia for laparotomy. The earliest inventor of general anesthetic in modern times was David the British chemist in the early 19th century.

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Anesthesia refers to a drug or non-drug method that temporarily or reversibly loses consciousness and pain in the body or the body. It is mostly used for surgery or for treating certain diseases. "Mabosan" is the first anesthetic invented and used in the world. It was created by Hua Yi, an outstanding medical scientist in the late Eastern Han Dynasty and the Three Kingdoms Period. In the 2nd century, China has used "Mabosan" general anesthesia for laparotomy. The earliest inventor of general anesthetic in modern times was David the British chemist in the early 19th century.

During the Eastern Han Dynasty, that is, the 2nd century AD, a famous Chinese medical scientist in ancient times

European and American doctors began to administer narcotics only in the middle of the 19th century, more than 1,600 years later than China. This is an incomparable initiative, which has made the medicine of the motherland far ahead of the world.

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Anesthetics commonly used in animal experiments are: volatile anesthetics, nonvolatile anesthetics, and traditional Chinese anesthetics.

1. Volatile anesthetic

Volatile anesthetics include ether, chloroform, and the like. Diethyl ether inhalation anesthesia is applicable to all kinds of animals. The difference between the anesthesia amount and the lethal amount is large, the safety degree is also large, the depth of animal anesthesia is easy to grasp, and the anesthesia is quicker to wake up. The disadvantage is that it has a large local stimulus effect, which can cause increased secretion of upper respiratory mucosal fluid, and then can affect breathing, blood pressure and heartbeat activity through nerve reflexes, and easily cause suffocation. Therefore, someone must take care when inhaled with ether in ether Too deep and the situation is happening.

2. Non-volatile anesthetic

There are many types of non-volatile anesthetics, including phenobarbital sodium, pentobarbital sodium, thiopental sodium and other barbituric derivatives, ethyl carbamate and chloral hydrate. These anesthetics are easy to use, can maintain a longer anesthesia time with one administration, the anesthesia process is more balanced, and the animals have no obvious struggle. The disadvantage is that it is slower to wake up.

3 Chinese medicine anesthetic

Sometimes used in animal experiments

According to their scope of action, they can be divided into general anesthetics and local anesthetics. General anesthetics and local anesthetics can be divided into inhalation anesthesia and intravenous anesthesia according to their different characteristics and methods of administration.

It is important to note that narcotics and narcotics are two different concepts. Narcotics refer to drugs that can make people unconscious, mainly pain.

Habitforming drugs refer to drugs that are prone to physical dependence and addictiveness after continuous use, and their use and storage should be strictly managed.