What factors affect a sufficient dose of rifampicin?
The establishment of a sufficient dose of rifampicin depends on a number of factors, including the condition for which it is used, the patient's weight and its renal and hepatic function. Rifampicin is an antibiotic drug used in combination with others to treat tuberculosis (TB), for many other bacterial infections and to prevent meningitis in endangered people. According to the manufacturer, it is only available in most countries and can be known under various trade names.
Rifampicin works by inhibition of rna-polymerase, enzyme involved in bacterial synthesis. By blocking the effect of the enzyme, Rifampicin prevents the replication of bacteria. When rifampicin is used to treat bacterial infections, including tuberculosis, it is used in combination with other antibiotics to prevent resistance. In the treatment of tuberculosis, the doctor may take a patient from a patient such as sputum to create bacterial susceptibility and allow the proper choice of drugs for treatment.
Rifampicin dose for the treatment of tuberculosis is usually determined ona kilogram basis in children and adults. In case of severe liver or kidney failure, rifampicin dose may be slightly reduced. In the case of severe tuberculosis or that they affect organs other than lungs, a higher dose of rifampicin may be administered and the course of treatment may be for a longer period of time. The treatment of tuberculosis is usually for many months with a number of different drugs, including rifampicin.
For the treatment of asymptomatic carriers of meningitis is a dose of rifampicin in adults usually 600 mg twice daily for two days. The dose for children is again determined by weight. Rifampicin is not used to treat meningitis, but to prevent it.
may be resistance to rifampicin and for this reason Counter Rifampicin is fully prescribed and other prescribed medicines must be completed even if the symptoms have been resolved. For this reason, repeated cultures can also be performed on patient samples. If there is a resistance, a change may be requiredtreatment.
As with any drug, rifampicin can interact with other medicines and cause adverse effects. Any other medicines, including complementary, over -the -counter and homeopathic products, should be communicated to a medical physician. The adverse reactions that have been reported include liver toxicity, gastrointestinal side effects and coloration of body fluids such as tears and urine. If any side effects occur, medical care should be required.