What Is a Nicotine Vaccine?

Smoking vaccine, also called nicotine vaccine, is a vaccine that can produce immunity to nicotine. Developed by scientists at Will Cornell Medical College in the United States. It can help smokers quit smoking, and it can also prevent non-smokers from developing such bad habits.

Smoking vaccine

Smoking vaccine

In June 2012, scientists at the Will Cornell Medical College in the United States developed a smoking vaccine that can help smokers quit smoking, and prevent non-smokers from developing such bad habits. This is a "one-for-all" vaccine that gives recipients a lifetime immune response with a single injection.

This research is currently in animal experiments.

The "smoking vaccine" is expected to be tested in humans by 2014 at the shortest and will be available before 2017.

Research experiment

During the research, scientists injected the gene sequence of the nicotine antibody into a genetically modified adeno-associated virus (AAV) that would not harm the human body. After injection, the vaccine enters liver cells, and the antibody's gene sequence enters the nucleus, prompting these cells to continuously produce antibodies and remove nicotine from the blood.

Research results

Researchers injected ordinary mice with virus-immunized mice and compared nicotine levels in their brains. The study found that immunized mice had 85% less nicotine in their brains than those who had not been immunized, and that the former's behavior, blood pressure and heart rate were not affected by nicotine.

The research report is published in the journal Science-Translation Medicine.

In July 2012, scientists at Will Cornell Medical College in the United States developed a new type of nicotine vaccine that can help smokers quit smoking, while also preventing non-smokers from developing such bad habits. This is a "one time and forever" vaccine that allows recipients to develop an immune response throughout their lives with a single injection.

First, this is a

First, this vaccine can be used to help smokers quit. After the smokers have been injected with this vaccine, if they smoke again and are affected by the vaccine, they will find that their bodies can no longer produce pleasure, which can help them quit smoking.

2. Prevent non-smokers from becoming addicted to nicotine, further reduce the number of smokers, and then curb smoking-related diseases. In particular, it can prevent children from becoming addicted to smoking.

Darren Griffin, a professor of genetics at the University of Kent in the United Kingdom, reminds us that human dependence on cigarettes includes both physiological and psychological aspects.

This vaccine is currently only a theoretical way to quit smoking. It still has to measure efficacy and risk, and it is temporarily impossible to determine a safe and effective injection dose. In the future, researchers will also perform experiments on mice, followed by primate experiments, and finally on humans.

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US researchers say that in the near future, smokers may be able to develop immunity to nicotine by injecting a smoking vaccine. In this way, they will not be able to experience any fun while smoking and will quit smoking soon.

This research is currently in animal experiments. Researchers injected mice with an injection that contained a genetically modified virus that turned the liver into a "factory" that continuously produces antibodies to nicotine.

Researchers said that the smoking vaccine is expected to be tested in humans within two years at the shortest and to be available in about five years. ^[2]