What are the factors of clotting?

Factors of coagulation or coagulation factors are a number of proteins present in the blood and which play the basic parts in the precipitation process. The total is 13 and are traditionally numbered using Roman numbers from I to XIII. When a blood vessel is cut, small blood particles called plates are collected at the injury and chemicals that activate the clotting of factors are released. The clotting factors then participate in the sequence of complicated chemical reactions, which end in the formation of a protein known as fibrin. Fibrin consists of a network of strands that combine with blood plates and blood cells and form a clot. It is also necessary that the clotting does not occur inappropriate, as the clot blocking a healthy blood vessel can lead to a reduced blood supply to body tissue. This could have potentially serious consequences if this tissue is part of an essential organ, such as the heart. There are chemicals in the blood that break down clots, and there is usually a general tendency to dissolve the clots. When the blood vessel afterIt is harmful and threatened with blood loss, the system moves towards the creation of clots.

Lack of factor clotting may cause bleeding disorder, where the cut is followed by excessive blood loss or where internal bleeding occurs. Deficiencies may occur when the collision of factors is not formed in reasonable amounts or if the specific clotting factor is defective and does not work. The causes of precipitation problems include some liver diseases, as many coagulation factors are carried out in the liver. Do not have enough vitamin K also reduce the level of coagulation factor, as vitamin is necessary to create some of the colored factors.

There are genetic disorders in which certain clotting factors are not carried out. Hemophilia A is a condition in which there is no factor of coating VIII, and in haemophilia B there is a lack of factor IX. Other shortcomings are rare.

Hemophilia can be treated tI miss the missing coagulation factors in the form of infusion into the vein. In cases where haemophilia is severe, it may be necessary to regularly administer clotting factors, while in milder cases the infusion may only be required if the bleeding occurs or in situations where it is expected, for example before surgery. With treatment, most individuals with haemophilia can expect a positive view.