What Are Muscarinic Receptors?

Muscarine is a natural alkaloid that is toxic and is mainly found in fungi belonging to the genus Scirpus and Physcomitrium , such as the hoarfrost. Fungi of the genus Pleurotus eryngii and Pleurotus eryngii have also been found to contain species that reach toxic doses ingested. Fungi of the genus Boletus, Umbellaria, Lactarius and Russula are also found to be harmless in trace amounts of muscarinic. Some fungi have variable muscarinic content, such as Amanita muscaria, which usually accounts for 0.0003% of the fresh weight. In contrast, the fungi muscarinic genus of the genus Filaria and Coprinus can reach 1.6%.

Muscarine

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Muscarine is a natural alkaloid that is toxic and is mainly found in the genus Filiaria and

Synonyms (middle): muscarinic, muscarinic, hemolysin

Chemical name: 2-Furanmethanaminium, tetrahydro-4-hydroxy-N, N, N, 5-tetramethyl-, [2S- (2, 4, 5)]-

Physicochemical properties: Chloride, C9H20ClNO2, coarse prism-like crystals (ethanol-acetone), very susceptible to moisture, melting point 180 1 °, [] 25 / D + 8.1 ° (C = 3.5, ethanol) Very soluble in water and ethanol, slightly soluble in chloroform, ether and acetone.

1. Choline-like effect: It has significant choline-like effects, exclusively acting on parasympathetic effectors after the festival. In cats and dogs, it has a significant effect on lowering blood pressure. In cats, the minimum dose of iodide to lower blood pressure is 0.004 g / kg.

2.

Muscatine is isolated and extracted from flytraps. Although this product is not used as a therapeutic drug, it has important pharmacological activities.

Muscarin is a classic M-choline receptor agonist, and its effects are similar to the symptoms of post-ganglionic cholinergic nerve excitation. Muscarine is originally extracted from flytraps, but its content is very low, but it contains high muscarinic ingredients in the genus Amphora and Coprinus. After eating these fungi, it can be used within 30-60 minutes. appear

Gastric lavage

2. Atropine 1 ~ 2mg, intramuscular injection every 30 minutes.