What is a harvester factor?
Atrial peat factor, also called the Hall of the Natriuretic Peptide (ANP), is a hormone produced in the heart of the heart in most mammals. Reduces the amount of sodium in circulation and lowers blood pressure. Like other hormones that control the balance of sodium and water, the harvest factor is an important part of the circulation regulation. High levels of narriuretic peptides are a clinical indicator of heart failure because the reduced circulation that characterizes the disease is partly due to their effects on blood pressure.
relaxed by cardiac cells that feel that the walls of the atrial walls, anp react to high sodium in circulation and angiotensin II, chemicals that increase blood pressure. The ANP is part of the family of peptide hormones that regulate the volume and pressure of the blood, as well as sodium and hydration levels. The brain peat peptide is another member of this group. Although it was discovered in pig's brains, this hormone is the ink -hints of the human heart where it has the same effects as a hall of the tentrous tentrum factor in the atria.
When it binds to receptors in the heart, kidneys and blood vessels, the peat factor of the atrium reduces blood pressure. It does this by dilatation of veins to reduce the volume of blood that reaches the heart. Anp also expands arteries, which reduces heart expenditure. In the kidneys, the ANP increases the filtration and excretion of sodium from the bloodstream and stimulates the release of hormonal renin. This chemical reduces angiotensin II and Aldosterone, two hormones that increase blood pressure and keep sodium in the body.
Natriuretic peptides are hormones that bind to peptide receptors located in their target cell membranes. They are made from the peat -up precursor C, are degraded by enzyme neutral peptidase and share the same peat and vasodilatory Effects. The clearance of sodium with kidneys increases urine output and creates these hormones diuretics. Some metabolic disorders may disrupt the feedback loop between the NatriuretIic peptides that reduce blood pressure, and hormones such as angiotensin II that increase it.
Clinically, the high level of the peat factor of the atrium is an important symptom of congestive heart failure. Shortly after the discovery of ANP in 1981, the levels of peat -up peptide have become a standard marker that shows heart extraordinary events in patients. In the case of heart failure, the peat factor of the brain and atrial is ex -regrrated, which seriously disrupts the normal feedback that regulates the blood volume drawn with the heart. Reduction of ANP levels is the aim of treating heart disease. Since neutral endopeptidase removes ANPs from circulation, several drugs have been developed on the basis of this enzyme to treat patients with heart failure.