What Is Cross-Reactivity?
Cross-reaction is that two antigens from different sources can have the same antigenic determinant between each other. The determinants stimulate the body to produce antibodies that can not only bind to the corresponding epitopes on their own surface, but also interact with another The same epitope of an antigen reacts and is called a cross-reaction.
Cross reaction
- This entry lacks an overview map . Supplementing related content makes the entry more complete and can be upgraded quickly. Come on!
- Chinese name
- Cross reaction
- Because
- Because of the common antigen
- Related
- Common antigen
- Related
- Common epitope
- Cross-reaction is that two antigens from different sources can have the same antigenic determinant between each other. The determinants stimulate the body to produce antibodies that can not only bind to the corresponding epitopes on their own surface, but also interact with another The same epitope of an antigen reacts and is called a cross-reaction.
- Because of the presence of common antigens, the antibodies produced by the A and B cells can not only bind to the corresponding epitopes on their own surfaces, but the antibodies produced by the A. bacterium stimulated bodies can also bind to the same epitopes on the surface of B. Similarly, the antibodies produced by the bacterium-stimulating organism can also bind to the same epitope on the surface of the beetle, but the response is weak. This type of antigen and antibody reaction is called a cross reaction.
- The formation of cross-reactivity may be related to the following factors:
- (1) Common antigen, some biological macromolecules of different organisms have the same antigen structure;
- (2) common epitopes, certain fragments (peptides) of different biological macromolecules have the same epitope;
- (3) Similar epitopes, different biological macromolecules, the partial spatial conformation of the epitope is very similar, and can be consistent with the complementarity determining region of the same antibody.
- The medical term explanation is: the reaction of antibodies or sensitized lymphocytes with different antigens with the same or similar epitopes is called cross-reaction