What is liver metabolism?
Hepatic metabolism is a number of chemical reactions that occur in the liver of the organism. It is part of the biochemistry of all types of vertebrates, including people, and is essential for their survival. The liver is a place of many vital metabolic processes, including protein synthesis, detoxification and digestive chemicals. Metabolism of liver is a source of many substances necessary for continued health and survival.
The liver is important for carbohydrate metabolization. The process called glycogenesis metabolizes normal sugar glucose and converts it into glycogen, which is stored as a compact energy reserve. If this energy is needed rapidly due to increased physical exertion or low blood sugar, the liver converts glycogen back into glucose in a process called glycogenolysis. Another metabolic pathway, gluconeogenesis, allows the liver to synthesize glucose from other substances such as lactic and glucogenic amino acid such as glycine and alanine. Metabolic processes in the liver transfer surplusCorner carbohydrates and proteins for chemicals called triglycerides, a primary form in which animals store fat. When the body needs energy, the liver breaks down triglycerides into free fatty acids that are released into the bloodstream, where they can be picked up and used as a source of energy by other tissues.
The liver synthesizes cholesterol to supplement diet cholesterol and produces lipoproteins that transport cholesterol by the bloodstream. It also metabolizes cholesterol to form bile acids, which are used to digest fats in the intestinal tract and the removal of metabolic by -products from the liver. Cholesterol is essential for healthy formation and maintaining cell membranes.
Theliver metabolism also produces amino acid and proteins. This is particularly important because the main source of blood plasma proteins in the blood such as serum albumin, soluble plasma fiBronectin and several types of globulin. The liver also produces most of the enzymes involved in the coagulation cascade, a process that causes the bleeding of blood clots as well as inhibitor proteins. Many supporting proteins are also produced by the liver, including ceruloplasmin, transport and haptoglobin.
hepatic metabolism is essential for protecting the body from substances from the outside of the body, called xenobiotics. The liver is the most important place for metabolic pathways that neutralize and remove foreign chemicals to a healthy biochemistry of the body such as poisons. Liver position in the front line, whenever a dangerous substance is ingested, causes damage to damage if it is repeatedly dragged and therefore the liver cirrhosis is a common effect of alcoholism.
Most of the metabolization of the drug also occur in the liver. Before reaching the bloodstream, the medication must swallow the patient to pass the liver. In some cases, the metabolism of the liver drug in the patient may prevent sufficient quantityHe knows the drugs to enter the bloodstream, which is a phenomenon called the effect of the first passage. Some medicines are administered by other means such as inhalation or injections to avoid this effect.
Many metabolic paths that are part of the liver metabolism are not covered by it and is also done elsewhere in the body. However, liver cells, called phagocytes, specialize for this function. Thus, the liver is the only most important place for these processes and the overall loss of liver function kills the body.
Many health problems may result if normal liver metabolism is disrupted. Due to the importance of liver production for blood protein production, people with liver damage may suffer from increased bleeding and bruises, shortness of breath as a result of reduced blood oxygen levels and potentially fatal renal failure caused by the lack of blood to the kidneys. Damaged body ability to process and eliminate chemicals can allow potentially hazardous substances such as ammonia, bilirubin andDifferent metals, build on toxic levels, causing health problems such as jaundice and encephalopathy.