What is the macrophage function?
macrophages are white blood cells that perform several key activities in the immune system. Although the usual function of macrophages is considered to support non -specific, congenital immunity, it also helps to launch specific defense processes. These cells are vital to the inflammatory response and can be induced to monitor individual targets such as tumor cells.
In the absence of foreign organisms, such as bacteria and viruses, is one of the functions of macrophages to absorb remnants and dead tissue. Macrophages meet this task in the same way as destroying foreign attackers, with a process called phagocytosis. During this process, the macrophage expands pseudo -pods to catch an object or organism, surrounds it and takes it to the body inside the vesic. The structure called lysosome then connects to the vesic and destroys the object of enzymes and toxic chemicals.
After performing phagocytosis, another macrophage function is obvious. Molecules on an attacker on the attacker who can be recognized by immune cells known asAntigens, is accepted by a macrophage and tied to a close auxiliary t cell in a process known as "presentation". By binding the antigen to a specialized molecule to its own surface, the macrophage ensures that other white blood cells do not intend to be an attacker. If the auxiliary t cell finds the corresponding antigen to the one presented by a macrophage, it will start an immune response.
macrophages are also involved in specific immune responses when they are admitted by T cells. This function of macrophages requires that compounds of release of t cells known as lymphokins in response to tumor cells or infected somatic cells. These compounds bind lymphokin receptors on the surface of macrophages and activate the macrophage to attack near cells.
Other functions of macrophages include an inflammatory response. After tissue injury, macrophages in the chemical area that promote blood flow to the area and cause inflammation. Inflammation, though painful, jE necessary to ensure that other macrophages and immune cells can arrive at the attack on potential attackers and clean dead cells.
After the injury, the second wave of macrophages arrives about 48 hours later, which does not participate in phagocytosis or inflammation. Instead, these macrophages release the factor to support the growth, repair of tissue and differentiation to help recover from damage to injury. The exact composition of this factor is not yet known, but the tissue injured when deprived of macrophages, tends to treat more slowly and provides evidence for its existence.