What Is the Amnion?
Amniotic membrane is a thin film composed of a single layer of epithelial cells connected to each other. Monolayer epithelial cells have the function of secreting amniotic fluid. As the embryo grows and develops, the amniotic membrane and villi closely adhere to each other, forming a fetal membrane. As the amniotic cavity gradually expands, the fetal membrane becomes a translucent film, which is non-vascular and rich in toughness (the fetal membrane is also the cyst wall of the amniotic cavity). The fluid in the amniotic cavity is amniotic fluid. The amniotic membrane covers only the decent placenta of the placenta and does not penetrate into the placental tissue. With the progress of pregnancy, the amniotic cavity gradually expands and occupies the entire uterine cavity. The amniotic membrane is the innermost layer of the fetal membrane and is a translucent film. The amniotic layers of the placenta and umbilical cord are connected. [1]
- Amniotic membrane is
- Preparation of amniotic membrane: Prenatal serological examination excludes hepatitis B virus (hbv),
- Patients with large limbal defects who have undergone amniotic membrane transplantation alone are not effective. They must be combined with limbal stem cell transplantation to better reconstruct the corneal surface structure. Ophthalmologists must recognize this, or the operation may fail. The end; preservation of amniotic membrane transplantation requires a certain amount of healthy bulbous conjunctival tissue in the recipient's eye, otherwise the amniotic membrane will not receive sufficient nutrition and support, and the graft will degrade prematurely and cause the operation to fail. This will make the amniotic membrane in a large area of the ocular surface Poor after-effect application of the disease; surgical timing of amniotic membrane transplantation for reconstruction of acute ocular surface burns
- Amniotic membrane
- However, as a new type of biological material, amniotic membrane has been used in ophthalmology, especially ocular surface diseases, and has achieved magical effects. It has a wide range of sources, low prices, simple material collection and storage, simple surgical operations and almost no immune rejection. , Very suitable for grassroots hospitals. It should be emphasized that the operation should be performed under the microscope, so that it can cleanly remove the diseased tissue and effectively reduce the surgical trauma. Whether the amniotic membrane also contains other unknown cytokines, the exact mechanism of several growth factors that have been detected is not yet clear; whether the various active ingredients in fresh amniotic membrane will affect internal eye surgery; Table reconstruction has the mechanism of inhibiting the proliferation of stromal cells and inhibiting the formation of new blood vessels for further study. These also need the unremitting exploration of basic eye researchers and ophthalmologists. It is believed that with the development of other related disciplines, with the joint efforts of the majority of ophthalmologists, amniotic membrane will have more amazing functions applied to ophthalmology clinics.