What is the function of estradiol?
estradiol is the strongest type of estrogen and is found in both men and women. Estradiol is often referred to as E2, maintains the health of reproductive organs and facilitates the fertilization process in women. In both sexes, E2 plays a role in protecting heart, bones and brain. While estrogen levels fall dramatically in women after they undergo menopause, they rise slightly in men when they are older. Estradiol was therefore associated with several diseases that tend to occur later in life.
As a sex hormone, E2 has several different functions in female fertility. First, it helps build and protect the lining of the fallopian tubes, vagina and uterus. This role is crucial for the embryo to connect to the uterus wall. Many women who have fertility problems have a low level of estradiol. Second, E2 keeps oocytes or egg cells in the ovary. Healthy oocytes lead to healthy embryos. Only the best oocytjood is selected at each ovulation.
It seems that as a tissue creator, it helps to protect women from heart disease by increasing HDL levels, "good" cholesterol in the body. When hormone levels fall in menopause in women, their risk of heart disease increases. E2 also helps to protect bone density in both men and women by participating in a system of messages that suppresses too rapid growth of immune cells in the bone. If multiple immune cells are allowed to grow, they may block calcium absorption in the bone. Therefore, it has been found that men with a lower level of this hormone are more susceptible to hip fractures.
Cancer was also associated with changing level E2 in both men and women. In men whose production of estradiol is increasing during aging, the hormone was held at least partially responsible for the higher risks of prostate cancer. In women, estradiol was associated with breast and endometrial cancer, uterine lining cancer. Older men lose protection from E2 as their hormonal balance changes. LevelEN circulating testosterone in their systems is no longer enough to block excess E2 levels. Women who have ceased to menstruate and therefore release endometriosis have also ceased to release excess estradiol. Although they produce lower hormone levels in all, it can accumulate over time. Some men and women decide on hormonal therapy to help reduce the risk of getting these diseases.