How is it related to dopamine and norepinephrine?
dopamine and norepinephrine are connected together with serotonin because they are three very important neurotransmitters that are the main components of monoamine neurotransmitter groups. All three are indicated by being potentially affected when a disease such as depression, and where the levels of any of the three can be lower than usual. It might seem that every neurotransmitter is produced in itself, but in fact dopamine and norepinephrine have a special relationship with each other.
As scientists continue to learn more about dopamine and norepinephrine, it is quite clear. In the absence of dopamine, norepinephrine is unlikely. Dopamine specifically creates norepinephrine using other chemicals such as beta-hydroxylase. Low dopamine levels tend to indicate low levels of norepinephrine and the absence or close absence of these chemicals in accordance could lead to very serious depression or anxiety.
With regard to this pharmaceutical compania hard pThey rained on the development of new types of antidepressants that affect dopamine and norepinephrine receptors. One of them is the successful Wellbutrin® or Zyban® (bupropion), called Norepinephrin Dopamine Norepinefrin Dopamine inhibitor. For some people, this NDRi has well tame depression and Zyban® was used as a smoking aid.
4 In fact, there are several. The most famous is the popular attention disorder (ADD) of Ritalin® drugs (methylphenidate). Some people with depression respond to the inhibitor of dopamine reuptake, but others seem to react more to the NDRI or other medicines that stimulate or inhibit serotonin reuptake.When they are in a good offer, dopamine and norepinephrine can affect the mind in a positive way. Norepinephrine can help regulate stress, help people feel pleasure, keep people attentive and help in learning and normal emotional developmentoji. Dopamine also helps people perceive pleasure, concentrate, think more clearly, maintain a even mood, remember things and learn new behavior. Together, both can disrupt rewards caused by hazardous substances such as cocaine or nicotine, which explains why Zyban® has been sold as finished smoking, although it is not entirely successful.
can be too many good things and have too much of these two neurotransmitters can be disastrous. If dopamine increases supplies, it can stimulate more norepinephrine production, which could lead to tremors, anxiety, mania, paranoia or other extremely undesirable features. The balance must be correct, or dopamine and norepinephrine can cause confusion on brain and body. Nowhere is it better proven than when people with bipolar disorder are treated with NDRI; Most of them progress quickly to manic states.