What are the different genotypes of hepatitis C?

There are six main genotypes of hepatitis C called 1, 2, 3, 4, 5 and 6. Hepatitis C is a crucial disease caused by a liver virus (HCV). The virus attacks the liver, often without symptoms for many years, and can eventually cause liver infection, scarring and eventually failure. However, all genotypes of hepatitis C can be managed by treatment, although accurate indications may change depending on genotype and subtype. Genotypes of hepatitis C 1, 2 and 3 are the most common and 2 and 3 have the most successful treatment speeds. sex; Transfusion of blood and organ transplantation before HCV screening; Dirty tools for medical use, piercing or tattoos; or in the uterus from mother to child. The first sixth months after the infection is called the acute phase and is the time when the disease is most treatable. However, most people do not experience any symptoms and non -skills during this time until they have developed into their chronic phase and began to cause the scarring of the liver. Symptoms during the acute phase mimic mild symptoms of influenza and chronicHepatitis C can be characterized by jaundice, nausea, reduced appetite, fatigue, joint pain, mood changes and problems. As the disease proceeds to cirrhosis or extensive scarring, it can cause veins or varicose veins, the accumulation of fluid in the abdomen or ascites, dwarf function of the liver and confusion or coma.

Hepatitis C virus is a very small RNA virus or virus that uses RNA as its genetic material. Different genotypes share the same basic form of the virus, with RNA inside and an outer layer composed of proteins and enzymes, allowing the virus to bear the liver cells for reproduction.

different genotypes of hepatitis C have a slightly different genetic make -up, but to allow the virus to avoid scientists' attempts to develop a vaccine that will work against all genotypes of hepatitis C and many subtypes. While the genotype can determine the duration of treatment and the probability of success, it does not represent the scopeliver damage. Some studies have also indicated that different genotypes can respond differently to different types of interferon treatments.

Genotypes of hepatitis C 1, 2 and 3 are the most common genotypes, especially in the United States. HCV 1 has two subtypes, 1a and 1b. 1a is the most common type of hepatitis C in North and South America and 1b is the most common type in Europe and Asia. It is more difficult to heal than genotypes 2 or 3 and are usually treated with higher doses of ribavirin or interferon for a longer period of time. Genotype 2 has three subtypes, 2A, which are common to China and Japan, 2b, which is common to the United States and Northern Europe and 2C, which is common southern and Western Europe. Genotype 3 is the most common in the South Pacific. Both genotypes of hepatitis C 2 and 3 have shorter treatment periods, usually around six months, lower doses of ribavirin or interferon and higher rate of cure.