What causes neuroblastoma in children?

neuroblastoma in children is caused by neuroblasts that do not ride. They do not become normal nerves or adrenal cells in which they should ripen at birth. These immature neuroblasts form a tumor. At birth, these neuroblasts should develop into nerves and adrenal glands that produce nerve fibers and adrenal glands. In most newborns, a small number of immature neuroblasts do not happen and usually disappear. In some infants, these neuroblasts remain and form a cancer tumor.

neuroblastoma in children is usually present at birth. However, it is often not determined until the tumor appears and causes symptoms. Most of the affected children are diagnosed until they are 5 years old. In rare cases, a malignant tumor in ultrasound is detected before birth, but it is not common to find tumors before age 1. The short end of this chromosome has a missing or rearrangement part. This causes extra reinforcement onkoa gene known as MyCn. Oncogen is a gene that causes cancer by making the cell malignant. MYCN amplification leads to unregulated and rapid growth of cancer cells.

Some children inherited genes, from one or both parents, which increases them the likelihood of obtaining cancer. In neuroblastoma in children, conditions such as fetal hydantoin and neurofibromatosis syndrome often lead to neuroblastoma. Initial genetic abnormality exists in conception and then the second abnormality at birth active.

tumors that grow with neuroblastoma in children usually begin in the nerve tissue of the pelvis, chest and/or neck. Tumors can also grow in the adrenal tissue. The telescopic glands sit on the peak and create the hormones that the body needs.

neuroblastoma spreads rapidly. It can quickly spread to other parts of the body. Most neuroblastoma cases in children also lead to other metastateto the carcinoma. Metastatic tumors of lungs, bones, lymph nodes, bone marrow and liver are common.

neuroblastoma treatment in children will vary depending on the size, location and level of tumor growth. It is most often recommended that surgery to remove as many tumors or tumors as possible. From now on, radiation and chemotherapy will help kill all the remaining cancer cells. In some cases, cancer cells cannot be completely killed, but can be forced to dormancy with aggressive treatment.