What is Enteropathica's Angrodermatitis?

children who have genetic problems with zinc absorption suffer from a condition called acrodermatitis enteropathica. Symptoms include heavy rashes, especially around the mouth and rectum and diarrhea. The child's diet adds symptoms, although the condition is lifelong.

Although the exact genes involved in inherited lack of zinc are unknown, scientists suspect that SLC39A4 can be involved. This gene -of -transport gene code, known as Zip4, which moves through zinc through membranes. Children with genetic condition cannot effectively move zinc from milk through the intestinal membrane. The disorder is recessive, which means that the child must inherit one copy of the mutated gene from each parent to have a disease. If it inherits only one bad copy, zinc metabolism is not affected.

Acrodermatitis enteropathica Symptoms usually arise in the first days or weeks of the child's life if fed with artificial milk. Babies who are breastfeeding do not show symptoms until they are shut down on solid Jídla. This difference is due to the fact that zinc from human milk is much more easily absorbed by a child than zinc from cow's milk. The rash begins as scaly, dry skin and turns into a lesion. Diarrhea is another common symptom.

Hair loss is another symptom of Enteropathica syrodermatitis, with affected algae and eyebrows. The child's nail area can be ignited and the nails can develop combs. The tongue can be red and glossy and ulcers can evolve in the mouth. The influence that has a disease on the baby's skin can also lead to secondary infections by yeast or bacteria and the wounds do not heal as normal as normal.

Zinc is ansential for normal body functions, so children affected with Enteropathica acreatitis can also suffer long -term damage if they do not receive zinc supplementation. Strong growth, neurological symptoms and infections are a complication of zinc deficiency. Affected childrenAs a result, they are usually irritated and emotionally depressed.

The symptoms of the disease begin to clarify as soon as the zinc is served. Prior to the discovery of zinc deficiency as the causes of the condition, children died within a few years of birth. Now, however, zinc supplementation throughout life can prevent enteropathtics of acrodermatitis to cause any damage. Children without inherited lack of zinc, but who do not gain enough zinc in their diet, can also suffer from similar conditions.