What Is an Echovirus?

ECHO virus is an abbreviation for enteric cytopathic human orphan virus. It was called an orphan virus because it was unknown when it was first isolated in 1950.

ECHO virus

ECHO virus can cause a variety of human diseases, from light

1. Asepticmeningitis is caused by the Coxsackie Group B virus and the common A7, A9, and ECHO viruses. Early clinical symptoms include fever, headache, general malaise, vomiting and abdominal pain, mild paralysis, and neck stiffness and meningeal irritation symptoms after 1 to 2 days.

2. Herpes angina (herpangina) is caused by A2 ~ A6, A8, A10 in Coxsackie A group. Typical symptoms are fever, sore throat, soft palate and vesicular ulcers around the uvula.

3 Hand-foot-mouth disease is caused by Coxsackie's A16 and neo-enteric virus 71, and sometimes A5 and A10. It is characterized by mouth and pharynx ulcers, herpes on the palms and soles of the feet, and can sometimes spread to the arms and legs.

4 Myocarditis Primary myocardial disease in adults and children is caused by the Coxsackie Group B virus, which accounts for approximately 5% of heart disease. ECHO virus 1, 6, 9 and other types can also be caused. Neonatal infections often cause death, and those infected at other ages can cause significant heart damage, and persistent infections can occur, triggering autoimmune responses that cause cardiomyopathy.

5. Infant systemic disease This is a very serious, multi-organ infectious disease that includes the heart, liver, and brain. Caused by Coxsackie Group B virus through placental infection of the fetus or contact infection caused by improper care. Some types of ECHO virus can also be caused. Infants often have symptoms such as drowsiness, difficulty in pumping, and vomiting, with or without fever, and progress to myocarditis or pericarditis, or even death.

Also. Coxsackie virus and ECHO virus can also cause respiratory infections, gastrointestinal diseases, chest muscle pain and other diseases, which may also be related to type I diabetes. After being infected with Coxsackie virus and ECHO virus, humans can produce specific neutralizing antibodies, and have long-lasting immunity to homologous viruses. Microbiological examination and prevention of virus isolation Take throat swabs or throat swabs, feces, conjunctival swabs and other specimens, inoculate primary or passage monkey kidney cells, culture for 5 to 14 days, observe cytopathological changes daily, and use standard serum to identify viruses Or inoculated suckling mice, the virus in group A often appeared within 3 to 8 days, and the virus in group B often appeared within 5 to 14 days, and then identified according to pathological damage and immunological methods. Serological tests can use immunofluorescence to detect antigens in cells, or ELISA to detect antibodies. RT-PCR can also be used to detect its specific nucleic acid fragments. No vaccines or drugs are currently available to prevent and treat Coxsackie and ECHO infections.