What Is an Epidermodysplasia Verruciformis?

Verrucous hyperplasia, also known as verrucous hyperplasia, is thickened in the epidermis, keratinized and thickened, protruding like a mountain or apex, and the dermal papillae may not protrude from the skin plane, and may also be accompanied by papillary neoplasia. It is common in the oral cavity, especially the gums, cheeks, and tongue. In addition, hands, feet, and penis are also visible. Clinically, it is often accompanied by white spots, and histology often has keratosis and epithelial atypia. It is worth noting that verrucous hyperplasia and verrucous carcinoma cannot be distinguished clinically. The two lesions often appear simultaneously and require a histopathological diagnosis.

Basic Information

Chinese name: Verrucous hyperplasia
Foreign name: verrucous hyperplasia

Object: Common warts, verrucous moles
Features: The skin looks like a mountain

Causes of Verrucous Hyperplasia

Common diseases that can be accompanied by verrucous hyperplasia are: verrucous nevus, verrucous extremity keratosis, common warts, verrucous skin tuberculosis, seborrheic keratosis, solar keratosis, sebaceous nevus, etc.

Clinical manifestations of verrucous hyperplasia

Common wart

Occurs in the back of the hands, feet, fingers, etc., mainly manifested as grains to soybean-sized nipples, rough surface. Pathological examination: hyperkeratosis, verrucous hyperplasia, etc.

2. Verrucous mole

Occurs on one side of the trunk and extremities. It is mainly linear or band-shaped, consisting of hard patches and pimples. The surface is markedly keratinized, light brown or dark brown. Pathological examination: incomplete keratosis, verrucous hyperplasia, etc.

3. Verrucous skin tuberculosis

Occurs in the hands, feet, arms, and extremities. It appears as a wart-like hyperplasia with atrophic scars in the center and inflammatory erythema around it.

4. Verrucous keratosis

Occurs on the back of the hands and feet, showing a wart-like papules the size of millet to soybean size. Pathological examination: hyperkeratosis, verrucous hyperplasia.

5. Seborrheic keratosis

Occurs on the face, limbs, and trunk, mainly as brown warts with clear edges and fatty scales. Pathological examination: hyperkeratosis, verrucous hyperplasia.

6. Solar Keratosis

Occurs in exposed parts of the face, ears, back of the hand, neck, etc., mainly manifested as raised wart-like patches, which are hard, dry and horny.

7. Sebaceous nevus

Occurs on the scalp and face, mainly with wart-like bulges with clear edges, enlarged sebaceous glands on the surface, and no hair.