What is creatine kinase?
creatine kinase, or CK, is found mainly in the brain, heart, skeletal muscles and other tissues. CK, also called phosphocreatin kinase or CPK, helps cells to produce a biochemical reaction that results in high -energy molecules that use cells to perform normal functions. When creatine kinase is combined with adenosine triposphate (ATP), it produces phosphocreatin and adenosinriptosphate (ATP). The muscles use these energy molecules to download muscle fibers. This reaction can also work the other way around so that phosphocreatine and ADP can create atp. CK-MM is produced by skeletal muscle, CK-MB is produced by the heart and CK-BB is produced by the brain. Under certain circumstances, CK-MM can escape the cells and enter the bloodstream. This occurs when the muscle is damaged, either by muscle injuries, exercise or a neuromuscular disorder.
doctors can test for the presence of the bloodshery kinase in the blood that helps diagnose and evaluate the disease in which mIt can cause muscle degeneration. A sample of sera blood and TA levels measured in the enzyme units per liter is obtained. The levels usually differ depending on gender, activity level and other factors, but the normal range is 22 to 198 units per liter.
high levels of creatine kinase can indicate neuromuscular diseases such as muscle dystrophy. Increased TA may also indicate heart attack, acute kidney failure, polymyosotis, dermatomyositis, hypothyroidism, hypothermia, recent surgery or recent session of intensive exercise. In the case of neuromuscular disease, high levels of CK can diagnose the disease before the appearance of other symptoms.
In cases of rabdomyolos, muscles decay very quickly and release the cellular content into the bloodstream. When this happens, the levels of creatine kinases can rise very much, indicating a dangerous condition where types can enter the kidneysproteins called myoglobins. Kidney failure may occur. Rhabdomyolosis is not in itself a condition, but a symptom of other conditions in the body. This is most often done after severe injury or as a result of the drug and requires immediate medical attention.
people who take statins to check cholesterol may have to regularly monitor TA levels. The side effect of statins is the pain and weakness of muscles, which in rare cases can lead to rabdomyolosis and the risk of kidney failure. Close monitoring of creatine kinase levels can alert a doctor of early signs of muscle breakdown, so that kidney damage can be prevented.