What is monoclonal gamopathy?
monoclonal gamopathy concerns a state in which the plasma cells of a person produce an abnormal type of protein called monoclonal immunoglobulin or m protein . The presence of M protein usually does not cause health problems, although in sufficiently large quantities can lead to the type of blood cell cancer known as multiple myeloma. Since there are usually no physical symptoms related to monoclonal gamopathy, doctors usually recognize the condition only after screening of blood samples for other problems. Treatment is not necessary, although people diagnosed with monoclonal gamopathy are encouraged to plan regular checks with their doctors to make sure they do not develop cancer.
Plasma cells are specialized white blood cells found in the bone marrow. They produce a number of important antibodies and other proteins that allow the immune system to function properly. Due to random mutation in certain plasma cells, they begin to produce a lot of proteins. AppearanceEM to the fact that scientists are not sure what these proteins really do, often refer to the state as monoclonal gamopathy of undetermined meaning . Proteins seem to prevent the functioning of the immune system unless there are extremely large quantities.
massive amount of protein can prevent other important white blood cells and proteins. The risk of cancer of blood cells and bone marrow increases with increasing the number of m proteins in the body. Some cases of monoclonal gamopathy proceed to multiple myeloma, especially devastating cancer that prohibits plasma to create new antibodies. Multiple myeloma can lead to anemia, kidney failure and heavy bone problems.
monoclonal gamopathy is the most common in people over 50 years of age and the risk of the state is constantly rising as people still age. Research suggests that it is more likely in men than in women. A doctor may diagnoseTicking monoclonal gamopathy I take blood and urine samples for laboratory examination. Analysis of blood samples can detect abnormalities in plasma cells and provide an exact number of m proteins in the bloodstream. Other tests, such as bone marrow biopsy and X -rays, can help doctors exclude multiple myeloma and other cancer in diagnosis.
Most patients with condition, especially if the number of M proteins is very low, does not need medical treatment. They are often obliged to plan regular checks with their doctors to monitor the procedure of the failure. Doctors analyze blood samples at regular intervals, usually every six months to check the presence of multiple myeloma and other cancers. Notice of cancer warning signals is necessary in providing the most effective treatment.