What Is Ototoxicity?
Ototoxicity refers to the structural and functional damage caused by the harmful effects of toxicants, drugs or certain physical factors on the ear organs such as the cochlea, vestibular and auditory systems.
Ototoxicity
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- Ototoxicity refers to the structural and functional damage caused by the harmful effects of toxicants, drugs or certain physical factors on the ear organs such as the cochlea, vestibular and auditory systems.
- Toxicity caused by drugs, also known as ear drug poisoning. Antimalarial drugs such as quinine and chloramidine can damage the hair cells and nerve cells of the spiral organs and cause neurological deafness, as well as congenital deafness. Streptomycin mainly acts in the vestibular system, and dihydrostreptomycin mainly acts in the cochlea. Ototoxicity caused by drugs is related to factors such as dosage, medication time, and individual sensitivity. Toxic substances such as ethanol, mercury, lead, carbon monoxide and noise can also cause ototoxicity., [1]