What is an anticoagulant?
Citrate Anticoagulant is used to thinner blood and prevent clotting. Unlike many anticoagulants, citrate anticoagulants cannot be administered directly to the patient, even if they may enter the patient's body when mixed with blood administered as a transfusion. The primary use for this type of anticoagulance is the prevention of clot in the blood that is held in tubes or transfusion bags. Citrate anticoagulants by tieting into calcium, which is the mineral needed for a thrombin cascade, stops blood clots. The trombin cascade is a number of chemical interactions that cause a blood clot.
The administration of citrate anticoagulants directly can pose a serious health risk to the patient, so they are only used to prevent blood clots that are outside the body. The filter installed in blood transfusion bags removes some of the calcium citrate molecules from the blood before it reaches the patient. Although not all anticoagulants are removed, the remaining amount is usually notOst to significantly thin the patient's blood. However, patients suffering from some types of organ failure, such as liver failure, may be at risk of serious bleeding if they administer blood transfusion that has been treated with citrate anticoagulant.
There are two types of citrate anticoagulance. One is called anticoagulant acid citrate dextrose. This compound contains citrosic acid, trisod citrate and dextrosis. Citrate Trisod acts as an anticoagulant, while citric acid is used to ensure that blood is at the right pH. Dextrose in this mixture is useful as a source of energy and also helps to prevent red blood cell disintegration. Variations of this compound may include phosphate, to improve blood life or adenine to maintain high levels of adenosine triphosphate (ATP).
The second type of citrate anticoagulance is called anticoagulant citrate sodium.To sThe Loučenina uses sodium citrate for its ability to interfere with thrombosis. It is used in plasma collection, liquid in which blood cells are suspended. Sodium citrate helps keep blood thin in plasma extraction before cells and other solid ingredients return to the donor.