What Is a Citrate Anticoagulant?
The application of physical or chemical methods to remove or inhibit certain coagulation factors in the blood and prevent blood from clotting is called anticoagulation. Chemical agents or substances that prevent blood from clotting are called anticoagulants or anticoagulants. Such as natural anticoagulants (heparin, hirudin, etc.) Ca2 + chelating agents (sodium citrate, potassium fluoride)
Anticoagulant
- Applying physical or chemical methods to remove or inhibit some of the blood
- Anticoagulant
- Medical use: treatment
- Different anticoagulants have slightly different anticoagulant principles.
- Ethylenediaminetetraacetic acid (EDTA) has the same anticoagulant principle as citrate: it combines with Ca ions in the blood to form a chelate, causing Ca to lose its activity and interrupting the coagulation process, thereby achieving the purpose of anticoagulation.
- Heparin achieves the purpose of anticoagulation by strengthening antithrombin III, inactivating serine proteases, and preventing the formation of thrombin.
- Oxalate is formed by the formation of calcium oxalate through its oxalate and Ca ions in the blood, making it non-coagulant.