What is a negative inotrop?
Inotrops are a wide category of drugs that affect the contraction and rhythm of the heart. Drug is a negative inotrop if it slows down the heart rhythm and weakens the counter -weaker power. This action benefits those who have conditions such as hypertension or arrhythmia. This category includes three healing classes-blockers, calcium antagonists and antiarrhythmics-everydays with their own therapeutic advantages and disadvantages. Treatment with negative inotrop depends on the condition and side effects of the prospective drug.
There is a proportional relationship between heart rhythm and contraction force. Fast heart rhythms require more strength to spread blood through the heart. Negative inotrop medicines create the opposite condition where a slow heart rhythm is able to pump blood with less force. Caused by increased blood flow in arteries, hypertension benefits from weakening contractions. Tachycardia, the type of arrhythmia, where the heart beats too fast, can also cope with this medicine. Other treatment conditions include chronic heart failure and angina.
Beta blockers are the first type of negative inotrop. They are primarily prescribed for hypertension because they reduce blood pressure by reducing adrenaline in the heart and drugs belonging to this class include atenolol, metoprolol and bisoprolol. Conventional side effects include cold limbs, dizziness and blurred vision and potential serious side effects include swelling, bruises and ease of bleeding. Contraindications may exist in patients with diabetes, lung disease or upcoming surgery.
calcium antagonists can treat hypertension, angina and arrhythmia and have a negative inotrop effect when they block calcium that would go out and blood vessels. This action releases vessels and slows blood flow and requires less rhythms and contractions. Medicines in this class include verapamil, felodipine and amlodipine. Normal side effects include dizziness, low blood pressure and nausea, while potential serious effect includes damagesLiver. If these drugs are given to a patient with a heart condition that has proceeded too far, a negative antagonist can actually cause more damage.
The final class of the negative inotrop is antiarrhythmics. These drugs help treat arrhythmia or incorrect rhythms of the heart by normalizing heart rhythm and less likely to speed up. Flecainide, procainamide and disopyramide are examples of drugs. Antiarrhythmics are not recommended for patients who have previously suffered heart attacks. The smaller side effects include dizziness, nausea and shortness of breath, while a strong negative inotrop effect can cause another, potentially fatal heart.