O-cresol is also known as o-cresol, o-methylphenol, 2-methylphenol, 2-hydroxy-1-toluene, 2-cresol, o-hydroxytoluene; o-cresol is the second isomer of cresol . O-cresol is mainly used as a synthetic resin, and can also be used to make pesticides dimethyltetrachloro herbicides, pharmaceutical disinfectants, perfumes and chemical reagents and antioxidants. Its downstream products are mainly synthetic resins o-cresol phenolic resin, O-methylsalicylic acid, p-chloro-o-cresol, o-hydroxybenzaldehyde, 2-methyl-5-isopropylphenol and antioxidants. It can also be used as a diluent, disinfectant and plasticizer in the production of sebacic acid.
Colorless crystals. There is a smell of phenol. Melting point 30.9 Boiling point 191 Relative density 1.0273 Refractive index 1.5361 Flash point 81 ° C Solubility Dissolves in water about 40 times (water solubility reaches 3% at 40 ° C and 5.3% at 100 ° C). Soluble in caustic soda and almost all commonly used organic solvents
use
It is an important intermediate for pesticide and herbicides. It is also used in the synthesis of coumarin. It can also be used as a disinfectant, preservative, diluent in the production of sebacic acid
Dangerous Goods Transport Number UN 3455 6.1 / PG 2
WGK Germany 1
RTECS number GO6300000
F 8-23
HazardClass 6.1
PackingGroup II
Customs code 29071200
95-48-7 (Hazardous Substances Data) [2]
S36 / 37 / 39Wear suitable protective clothing, gloves and eye / face protection. Wear appropriate protective clothing, gloves and goggles or masks.
S45In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) In case of accident or if you feel unwell, seek medical advice immediately (show the label if possible). [3]
R34Causes burns. Causes burns. [3]
It is an important intermediate for pesticide and herbicides. It is also used in the synthesis of coumarin.
O-cresol is a synthetic pesticide, dye,
O-cresol is colorless or slightly reddish crystal, with
1. Molar refractive index: 32.95
2. Molar volume (cm3 / mol): 104.1
3. Isometric Zhang Rongrong (90.2K): 259.9
4. Surface tension (dyne / cm): 38.8
5. Polarizability (10-24cm3): 13.06 [4]
1. Hydrophobic parameter calculation reference value (XlogP): None
2.Number of hydrogen-bonded donors: 1
3.Number of hydrogen bond acceptors: 1
4.Number of rotatable chemical bonds: 0
5.Number of tautomers: 3
6. Topological molecular polar surface area 20.2
7.Number of heavy atoms: 8
8.Surface charge: 0
9.Complexity: 70.8
10.Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 0
13. Determine the number of chemical bond stereocenters: 0
14. Uncertain number of chemical bond stereocenters: 0
Carcinogenicity: Minimum percutaneous toxic dose (TDL0) in mice: 4800 mg / kg (12 weeks, intermittent), which is positive for tumors.
Environmental hazards: It is harmful to the environment and can cause pollution to water bodies.
Biodegradability: at a concentration of 11 to 16 mg / L in water,
Monitoring method
source
category
Gas chromatography
"Air and Exhaust Gas Monitoring and Analysis Methods"
Air and exhaust
Gas chromatography; chromatography / mass spectrometry
Handbook of solid waste test analysis and evaluation manual
Solid Waste
High performance liquid chromatography
"Determination of Hazardous Materials in the Air" (Second Edition), edited by Hang Shiping
air
Chloroimine dibromobenzoquinone colorimetry
"Determination of Hazardous Substances in the Air of Chemical Enterprises", Chemical Industry Press
Chemical Enterprise Air
[1]
China (TJ36-79)
Maximum allowable concentration of harmful substances in the air of the workshop
5mg / m
Former Soviet Union (1978)
Basic safe concentration in ambient air
28g / m
Former Soviet Union (1975)
Maximum allowable concentration of harmful substances in water
0.05mg / L
Former Soviet Union (1978)
Maximum allowable concentration in fishery water
3g / L
Former Soviet Union (1975)
Sewage discharge standards
0.1mg / L
Olfactory threshold concentration
0.00068ppm
[1]
Preventive measures: Safety procedures must be implemented and strictly implemented during the operation, storage, and transportation. Any operation of heating phenol should be closed, supplemented with suction equipment, pay attention to fire and explosion protection, and prevent skin contact. When washing phenol containers, personal protection should be strengthened. In the production workshop, flushing equipment is set at obvious signs for emergency water.
Skin contact: Take off contaminated clothing immediately, use
Isolate leaking contaminated areas and restrict access. Cut off the fire. It is recommended that emergency handlers wear self-sufficiency
O-cresol liquid
Small opening steel barrels; ordinary wooden boxes or semi-grate wooden boxes outside glass bottles or plastic barrels (tanks); threaded glass bottles; threaded glass bottles.
O-cresol solid
Fully or middle-opened steel barrels outside plastic bags or two-layer kraft paper bags; ordinary wooden cases outside plastic bags or two-layer kraft paper bags.
Store in a cool, ventilated warehouse. Keep away from fire and heat sources. Packaging is required to be sealed and not in contact with air. It should be stored separately from oxidants, alkalis, and edible chemicals. Equipped with the appropriate variety and quantity of fire equipment. The storage area should be equipped with suitable materials to contain spills. The "five double" management system for extremely toxic substances should be strictly implemented.
The railway transportation shall be carried out in strict accordance with the dangerous goods installation table in the "Dangerous Goods Transportation Rules" of the Ministry of Railways. Before transportation, check whether the packaging container is complete and sealed. During transportation, ensure that the container does not leak, collapse, fall, or damage. Mixed transportation with acids, oxidants, food and food additives is strictly prohibited. During transportation, it should be protected from direct sunlight, rain and high temperature.
The relevant dangerous goods shall be classified and transported in accordance with the requirements of the International Maritime Organization (IMO) when shipping. [5] . [6] .
