What is the difference between Enlapril and CaptoPril?
ENALAPRIL and CAPTopril are drugs used in the treatment of high blood pressure caused by hypertension, heart failure and other health conditions. These drugs function in a similar way and are classified as inhibitors of enzyme (ACE) with angiotensin due to their effect from preventing protein from ace to reduce the blood vessels of the body. There are some differences between these drugs, despite their similarities that may lead to doctors to prescribe one in certain situations. Enalapril can be administered to patients as a tablet to behave orally or can be injected intravenously (IV) for immediate action. Captopril, on the other hand, is always given to the patient orally, which means that it is usually not used to alleviate emergency hypertens crises.
The difference in the way the administrators of Enlapril and CaptoPrilrated has to do with their relative strengths. CaptoPril doses are higher, starting with 25 milligrams (mg) because it is considered a weaker medicine. Plus he has a stokerOral biological availability than enalapril, which means that in the absorption into the bloodstream more effectively when using the mouth. The initial active doses for Enlapril are 5 mg for oral use and 1.25 mg, if administered in the form of IV, due to its more effective means blocking ACE protein.
The duration of action is another point of differences between Enlapril and CaptoPril. Enalapril has a 19 -hour half -life, or a time that takes half of the drug to disintegrate and remove from the body after ingestion. The half -life of Captopril is only 1.9 hours, which is another reason not used in hypertensive emergencies. Shorter half -lives require further dosing at more frequent intervals, which is undesirable during a serious doctor.
The side effects of enalapril and capital show a certain variant. ACE inhibitors, including both of these drugs, tend to cause dizziness, hypotension and cough. Another sideHowever, the effects can be seen in a capital that are not present in other medicines of its class. It contains sulfur atom in its structure that other ACE inhibitors do not have, leading to unique potential side effects, including a rash and a persistent metal taste on the tongue that some patients experience. Postural hypotension or loss of blood pressure during rapid getting up, is another side effect that occurs only in the capital and exists due to the rapid speed of the onset of the drug.