What is Vinpocetin?
Vinpocetin is a drug synthesized from Vincamin, VINCA Minor L or periwinkle extract. It is identified by the chemical name Vinpocetin-ethyl apovincamine and is sold under various trade names such as Intelelectol and Cavinton. It is used to treat cerebrovascular disorders for decades in Japan, Hungary, Germany, Poland and Russia. Although it is still largely a prescription -based drug in Europe, it is available as a dietary supplement in the US and Canada. On the one hand, this increases blood circulation in the brain by an enzyme called phosphodiesterase. It also stimulates the production of adenosine triposphate (ATP), a substance that provides energy in nerve cells. This is significant because the availability of ATP tends to reduce with age and is the main cause of the death of nerve cells. Vinpocetin is also awarded for its nootropic effects, which means that it is formed as a memory amplifier.
It also improves the use of oxygen and glucose in the brain. Increasing hormones, noradrenaline and dopamine are also attributed. InterrogationThe DEK is that the concentration of serotonin and acetylcholine increases. The latter are found neuromodulators in virtually all autonomous ganglias, clusters of brain cells, which serve as bridges between the central nervous system and the peripheral nervous system.
In addition to increasing blood flow and neurotransmission in the brain, Vinpocetin also shows antioxidant and neuroprotective activity. Studies have shown that its presence in the brain will discourage the formation of free radicals and lipid peroxidation. It also seems to protect brain cells from the toxic effects of glutamate and n-methyl-d-aspartate. While studies on therapeutic benefits of this drug are still preliminary, scientists scientists that this may have the potential to treat or prevent ischemic stroke and Alzheimer's disease.
oral doses of vinpocetine usually enter the bloodstream within an hour, but are generally not well absorbed. While using herHowever, biological availability increases by 60-100 percent. However, studies have shown that it is best supplied intravenously and absorbed through the central nervous system. Even more importantly, these studies have shown that he is able to cross the blood barrier-molating. Once in the right neighborhood, the drug is easily occupied by thalamus and the core of Putamen and Caudate, the central part of the brain.
Vinpocetin may cause side effects in some people. The most commonly reported are the stomach, nausea, dizziness, headache and drought. In addition, this should not be used during pregnancy or nursing, people with seizure disorders, low blood pressure or people with a history of liver or kidney disease. It has vasodilation properties from Vinpocetin, should not be taken with blood weight loss or anti -aggregation drugs, including Coumadin (warfarin), aspirin therapy, garlic or ginkgo.