Why do I have to avoid using ciprofloxacin with milk?
oral drugs such as ciprofloxacin must get around the gastrointestinal barrier and into the body to be effective. Some meals and drinks, if they are eaten at the same time as medicines, may disrupt the absorption of certain drugs. Ciprofloxacin with milk is one of these situations and therefore doctors do not recommend this combination.
Every medicine has what is called "biological availability". This is the percentage of the drug in the method of delivery, which can get into the blood circulation of the body. The percentage of drugs that are not included in biological availability can be divided into other molecules or can pay off the body with urine or feces.
The 1991 University of Turku studies in Finland analyzed the biological availability of ciprofloxacin with milk and other dairy products. Each participant affected the study overnight and then ate yogurt or drank milk or water along with a dose of ciprofloxacin. Scientists tested the Party's Blood Part of the Participants over time. Found that those patients who only drank water hadHigher concentration of drug circulation than those who enjoyed ciprofloxacin with milk or ate yogurt. The concentration of the drug of the plasma milk drinker was almost half the concentration of water drinkers.
In 2010, scientists at Semmelweis University in Hungary found that the most likely culprit for this lack of absorption in the gastrointestinal tract was a protein called casein. Casein is a main part of milk and dairy products such as yogurt, and when it comes into contact with the medicine, it prevents absorption to the body. Ciprofloxacin product manufacturers take this research into account when they write instructions for users.
All drugs, including antibiotics such as ciprofloxacin, must be present in the body at specific concentrations in order to make their work properly. Ciprofloxacin kills certain types of bacteria such as those that cause legionelosis and some food poisoning, and low concentrations may notto clean the infection. Doctors therefore need to know how much the drug will do this work correctly and prescribe the dose accordingly.
Ciprofloxacin with milk together requires the patient to take more medicine to cure the infection. Because almost all drugs have side effects, doctors do not want to prescribe more medicines than necessary. The risk of side effects of this particular drug is such dangerous complications such as hallucinations, cracked tendons or changes in the rhythm of the heart. Possible complications for a patient taking ciprofloxacin with milk may include impaired infection.