What Are Steroid Hormones?

Steroid hormones, also known as steroid hormones. It has extremely important medical value. In maintaining life and regulating sexual functions, it has a clear role in body development, immune regulation, skin disease treatment and fertility control. The discovery and development of steroid hormone drugs is an important stage in the development of the discipline of medicinal chemistry.

Chinese alias: also known as steroid hormone.

English name: Steroid hormone.

1,

Steroids are a class of fat-soluble hormones that are structurally all cyclopentane polyhydrophenanthrene derivatives.

The mechanism of action of steroid hormones-

Steroid hormone biosynthetic pathway

Systemic steroid therapy, especially long-term or high-dose use, is often accompanied by many potential adverse effects. Skin side effects include

Regular checks of blood glucose levels, blood cell counts, guaiac stool stool blood (stoolguaiacs) and blood pressure are required. Diabetes, hypertension, pregnancy and mental disorders are contraindicated. The hypothalamus-pituitary-adrenal axis of patients who have been receiving long-term hormone therapy is inhibited, which is needed during surgery and other body stress.

Experts point out that hormones are the number one cause of necrosis of the femoral head. Femoral head necrosis is directly related to the type, dosage form and route of administration of the hormone, and is not directly proportional to the total amount and time of the hormone; one of the reasons for the occurrence of femoral head necrosis due to long-term use of large amounts of hormones or excessive daily doses, and mutations in dose increase and decrease In addition, it is also related to individual sensitivity, especially menopausal women, pregnant women are hormone sensitive, and related to the primary disease.

Clinically, the medium and long-acting hormones are more widely used than the short-acting hormones, have a longer half-life, and have a longer accumulation time in the body. Superphysiological applications can cause ischemic necrosis of the femoral head. The incidence of hormone injections is higher than that of tablets. When administered intravenously or epidurally, when the points around the joint are closed or injected into the joint cavity, the incidence of femoral head necrosis is high, the condition is severe, and the interval between onsets is short. This may be completely related to the full absorption and effect of the drug in the body.

Some diseases have to use hormones because of the need for treatment. However, it is terrible that they are misused or blindly abused because of insufficient knowledge. The number is amazing. Some even use hormones repeatedly for colds and fever of unknown cause. Some people mistake soft tissue strains and chronic degenerative arthritis as rheumatoid arthritis treatment, and long-term application of hormones can not help but arouse people's high attention.

In the end, experts remind everyone: it is understandable to use hormones for the treatment of diseases. The prerequisite is to use them under the guidance of a doctor. Do not use or abuse them by yourself. Now many prescription drugs can still be bought in pharmacies, then ask patients There must be a sense of not using hormones indiscriminately, and only in this way can we be as far away as possible from necrosis of the femoral head. ^[2]