What factors affect the secretion of antidiuretic hormone?
Antidiuretic hormone secretion (ADH), also called vasopressin, occurs in the pituitary gland and maintains water in the bloodstream. The main factors affecting its release is to reduce the amount of water in the plasma and increase the number of solid molecules such as sugar and salt, in the bloodstream. ADH works partly by causing the kidneys to reabsorb water rather than excluding it as a urine. When this process is disturbed, the results of diabetes insipidus. In the kidneys it controls changes in the permeability of tubules to prevent the excretion of salts and glucose. Production and secretion of antidiuretic hormone occurs in the rear pituitary gland of the brain, where it is one of only two hormones, the other is oxytocin. ADH is excreted whenever the body becomes hypovolemic of a significant loss of fluids.
When receptors in blood vessels are detected to reduce osmolarity in the plasma plasma, send signals to Medully braina tribe. Here, the nerves transmit information to the hypothalamus that controls the secretion of the pituitary hormones. Angiotensin receptors are placed on the hypothalamus so this hormone can also increase vasopressin secretion. The drop in blood pressure, which is detected by arterial stretch receptors, also cause ADH release. Brain centers that respond to blood pressure and osmolarity are those that modulate vomiting and nausea that increases the release of vasopressin in complex feedback.
The prevention of water excretion in the urine is the main function of vasopressin. Therefore, ingestion of diuretics causes compensatory secretion of antidiuretic hormone. When vasopressin activated, the Channels open water canals, which reabsorb water, which is otherwise excluded as urine. If ADH does not reach these channels and binds to receptors that control them, more water will be lost. Alcohol consumption can reduce the effects of hormone and cause water loss and dehydration because ethanol binds to ADH receptors in collection kanal, which blocks the action of hormone.
Insipidus diabetes is the result of problems with secretion of antidiuretic hormone. Central diabetes is caused when the hypothalamus, injured by trauma or under the pressure of the tumor, ceases to create chemicals that say pituitary gland to be adh. This can usually be treated by providing the patient with additional vasopressin. Diabetes Insipidus also leads when the receptors in the kidney collection channels do not respond to the antidiuretic hormone and the water channels remain closed. Patients with insipidus diabetes produce a large amount of urine due to their condition and experience thirsty as a result.