What Is Amino Acid Synthesis?
Most of the amino acids that make up proteins are biosynthesized by using the Embden-Meyerhof pathway and the intermediate of the citric acid cycle as the carbon chain backbone. The exceptions are aromatic amino acids, histidine, the biosynthesis of the former is related to erythrose-4-phosphate, an intermediate of pentose phosphate, and the latter is synthesized from ATP and phosphorophosphate pyrophosphate.
Amino acid synthesis
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- Chinese name
- Amino acid synthesis
- Foreign name
- amino acid synthesis
- Time
- June 2014
- Types of
- Unnatural chiral amino acid
- Most of the amino acids that make up proteins are biosynthesized by using the Embden-Meyerhof pathway and the intermediate of the citric acid cycle as the carbon chain backbone. The exceptions are aromatic amino acids, histidine, the biosynthesis of the former is related to erythrose-4-phosphate, an intermediate of pentose phosphate, and the latter is synthesized from ATP and phosphorophosphate pyrophosphate.
- Amino acid synthesis
- Most of the amino acids that make up proteins are biosynthesized by using the Embden-Meyerhof pathway and the intermediate of the citric acid cycle as the carbon chain backbone. The exceptions are aromatic amino acids, histidine, the biosynthesis of the former is related to erythrose-4-phosphate, an intermediate of pentose phosphate, and the latter is synthesized from ATP and phosphoribosyl pyrophosphate. Microbes and plants can synthesize all amino acids in the body, and some amino acids in animals cannot be synthesized in the body (essential amino acids).
- Essential amino acids are generally biosynthesized from intermediates of carbohydrate metabolism through multi-step reactions (more than 6 steps).
- In June 2014, researchers devised a simple synthesis method of "unnatural chiral amino acids". [1]
- Amino acid is a generic name for a class of organic compounds containing amino and carboxyl groups, and is the basic constituent unit of biologically functional macromolecular proteins. The molecules of unnatural chiral amino acids are "enantiomers", which play an important role in the fields of drug development, chemical synthesis, and catalysis. [1]
- Natural amino acids are cheap and readily available, but there are not many types, so non-natural chiral amino acids need to be synthesized. [1]
- According to the traditional synthesis method, each different non-natural chiral amino acid is synthesized using different starting materials, and their idea is to use the cheapest alanine as a common starting material to synthesize thousands. An unnatural chiral amino acid. [1]