What Is an Amyloid Precursor Protein?

Amyloid precursor protein (APP) is a single transmembrane protein widely present in tissue cells of the whole body. It is lysed by protease to produce toxic -amyloid protein. The true physiological function of APP is still poorly understood.

Amyloid precursor protein

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Amyloid precursor protein (APP) is a single transmembrane protein widely present in tissue cells of the whole body. It is lysed by protease to produce toxic -amyloid protein. The true physiological function of APP is still poorly understood.
Chinese name
Amyloid precursor protein
Foreign name
amyloid precursor protein
Short name
APP
Category
Single transmembrane protein
Amyloid precursor protein (APP) is a single transmembrane protein widely present in tissue cells of the whole body. Because of its cleavage by protease, it produces -amyloid (-amyloid, A), and it has received widespread attention, but so far people do nt know much about the true physiological function of APP. Many scholars think that the senile plaques formed by the deposition of A after APP cleavage are an important cause of AD [1] .

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