What is biological availability?
Biological availability is the term used by several sectors of scientific studies to describe the way chemicals are absorbed by humans and other animals. Biological availability was once strictly attributed to pharmacology, but now also has a wide application in environmental sciences. The exploration of the biological availability of a substance in pharmacological studies helps to determine the doses of specific drugs. Measuring the biological availability of the drug, when it reaches circulation in the body, describes aspects such as absorbent and half -life. It can also evaluate the supply of drugs.
intravenous administration of drugs is considered to be 100% biological availability because they do not pass through the stomach. They are immediately in the circulatory system. However, other drugs administered at the same time may reduce the effects of intravenous administration and affect its biological availability.> And relative biological availability . Absolute biological availability is the measuring of the drug as soon as it passes through the intestine and is released into the circulatory system. The relative biological availability is tErmine used to compare different formulations of the same drug, such as Versus General.
Some studies have found that some general products are not equivalent in biological availability for branded versions of drugs. One examples is a synthroid drug, which is usually launched in a general form like thyroxidine. Many patients who use thyroid substitution therapy find that thyroxidine is not as effective as synthroid. Technically, these two drugs should be equivalent, but in the studies there were differences in the biological availability of both forms. However, this will not change most of the insurance coverage in terms of this medicine. Generally one will still have to pay extra for buying a synthroid.
Other factors can affect biological availability when medicines are used orally. Slow or rapid metabolism can change the rate of drug absorption. Factors outside the body such as incorrect withLaying drugs can lead to less than expected results of biological availability.
Biological availability, if used in environmental sciences, evaluates the speed and amount of toxic substances that may occur in the body. One example is the recent concerns about the level of mercury in fish. Some fish contain high levels of mercury, poison that can lead to serious diseases when ingested in high quantities. People who eat a lot of fish can be subject to mercury poisoning. Recent US FDA recommendations propose high mercury fish no more than once a week.
Another study on biological availability, which has aroused concerns about our relationship with the environment, is the discovery of a small amount of fuel excreted in the human breast. At this point, no one proposed for mothers to stop breastfeeding their children, but the studies raise concern about many things we take for granted, such as flying aircraft or missiles, which can actually increase the risk of health problems for children andadults.
Biological availability studies can also compare animal or plants with the presence of toxic chemicals in the environment. It is worried about to what extent these chemicals are present in animals when they reach the circulatory system and what possible effects can have on animal populations.
For example, the populations of animals that were later consumed by humans were consumed by plant populations covered with DDT. Some effects in humans were an increase in certain cancers and autoimmune disorders. People could also consume DDT through plant material and create similar problems. These studies resulted in DDT bans, which was once commonly used as a pesticide.
Biological availability of toxins in our environment, when it is studied, can have a significant impact on our quality of life and choice. These studies are invaluable because they can help us approach our ecology with a sense of responsibility and an opinion on the future.