What Is Somatic Mutation?
Somatic mutations are mutations that occur in somatic cells other than sex cells. Does not cause genetic changes in offspring, but can cause changes in the genetic structure of some contemporary cells. Most somatic mutations have no phenotypic effect. Some somatic mutations in plants can cause changes in leaf shape and branch shape.
Somatic mutation
- Chinese name
- Somatic mutation
- Foreign name
- somatic mutation
- Definition
- Mutations that occur in normal body cells
- Genetic form
- Passed through gametes to future generations
- Somatic mutations are mutations that occur in somatic cells other than sex cells. Does not cause genetic changes in offspring, but can cause changes in the genetic structure of some contemporary cells. Most somatic mutations have no phenotypic effect. Some somatic mutations in plants can cause changes in leaf shape and branch shape.
- Somatic mutations are mutations that occur in normal body cells, such as mutations in the skin or organs. Such mutations are not passed on to future generations. Somatic mutations are not the same as germline mutations, which occur when they become
- The genetic form of a malignant tumor can be passed to offspring through gametes; however, the sporadic form of a malignant tumor can be caused by somatic mutation. There may be two types of transmission of the same malignant tumor. Tumors can be regarded as the result of abnormalities in the structure or function of genetic material of cells based on the genetic susceptibility of individuals, especially the genetic susceptibility of individuals to tumors. Most of these abnormalities are not inherited by germ cells, but are caused by new gene mutations in somatic cells. Mutated precancerous cells develop into tumors under the influence of some cancer-promoting factors. Therefore, some people think that most tumors can be regarded as a somatic genetic disease.
- In nature, gene mutations often occur. If mutations occur in genes related to cell proliferation, they may cause cells to get rid of normal growth control and exhibit the phenotypic characteristics of malignant cells.
- Many carcinogens are mutagens. Most of them can cause DNA damage. These damages can be repaired and cause cell death. If DNA repair is abnormal, cells can continue to survive, but become potential
- Some scholars believe that somatic cancer does not necessarily have a change in the genetic structure. When substances or factors other than genes such as proteins, RNA, and biofilms have changed, these changes can also cause genes related to growth and differentiation to abnormally close or At this time, the idea that cells can also be transformed into cancer cells is called the theory of extragene regulation. Recent studies on genetic imprinting have shown that gene modifications such as methylation can also affect the expression of tumor-related genes, thereby promoting cell transformation.