What are the high levels of bilirubin?
high bilirubin levels may be a symptom of liver disease in adults or older children, but it may be common in newborns. Bilirubin is a naturally occurring organic molecule that occurs in the bile, blood, urine and body fluids due to the decay of red blood cells. It is classified as a pigment that has multiple conjugated double bonds that absorb specific wavelengths of light, resulting in a color molecule. The yellow-green high level of bilirubin gives bruises, children, urine and bile their characteristic color. Like pigments used by plants for sensing light or certain algae to capture the energy of light, bilirubin consists of an open chain of four five -member, containing nitrogen, pyrollical rings. In the middle of a large ring lies the iron atom. Its condition of ionization determines the degree of attraction on oxygen molecules. After the death of red blood cells, the porphyrin ring breaks, the iron recovers for recycling and the remaining unnecessary residueThe molecule of the open chain of bilirubin is released into the surroundings. It is a waste product to be removed.
released bilirubin in its unconjugated form is not soluble in water, but is bound by albumin, the predominant plasma protein, for transport to the liver, where it is conjugated with glucuron acid. Most of this conjugated form is concentrated in the bile and released into the small intestine. A small amount can be released by urine. The presence of elevated bilirubin in the urine in its conjugated and unconjugated forms serves as an indicator of possible damage or liver disease.
The activity of the liver's blood detoxification is one of the last that will be fully functional in newborns because the diges of their Mother Systems has done this task for them. Within two to five days after birth, the newborn must take over the blood filtration. Meanwhile, the child could experience a high number of bilirubin to the extent that the whitesEyes and skin have a yellow shade. This is worrying because the brain blood barrier is not fully determined in infants and high levels of bilirubin can leave in the brain and cause neuronal defects. Lighting therapy in which the child is exposed to natural or artificial light sources for the period of the specified periods of time causes the ismerizing molecule sensitive to light, which is a change in geometric configuration, into a water -soluble form and can be excluded from the body in the urine.
In adults moderately elevated bilirubin levels are generally not harmful. It is assumed that five to 10 percent of the population has Gilbert's syndrome that causes lower activity in the enzyme that combines bilirubin. Other causes of high bilirland of the tank include the use of antipsychotic drugs and chemotherapy. Serious bilirubin levels are associated with bile ducts, cirrhosis or other liver disease.