What are the side effects of warfarin?
The side effects of warfarin include bleeding, necrosis, reducing bone density and purple tip syndrome. These side effects are often caused by interaction of warfarin either by common medicines and some foods. The side effects of warfarin must be carefully monitored to ensure that its dose is adequate and safe. During the early stages of warfarin treatment, the patient's daily blood tests may be necessary. The primary goal of this testing is to ensure that warfarin does not cause patient bleeding.
bleeding is one of the most common side effects of warfarin and occurs in up to 2.7 percent of cases. Before prescribing warfarin, the physician must always consider benefits against bleeding risks. Specific examples of bleeding due to warfarin include bruises, coughs of blood, nosebleed and bloody urine. The risk of bleeding further increases when warfarin is combined with non-steroidal anti-inflammatory drugs and anti-plates. Patients with hemodialysis and older people are exposed to warfarin useand increased risk of bleeding.
necrosis is one of the rare side effects of warfarin, which primarily affect the skin and limbs. Most likely, it is in patients who have a lack of protein C, another anticoagulant that requires vitamin K. Warfarin initially lowers the level of protein C in the blood faster than reduces clotting factors. This can lead to massive blood clots that can cause necrosis and gangrene. Patients endangered from warfarin necrosis usually receive heparin in conjunction with warfarin.
Bone density, also known as osteoporosis, can also be one of the side effects of warfarin. The 1999 study, including 572 women with Warfarin, showed an increase in the fracture of the ribs and the vertebral column. Another study of men in 2006 combined the use of Warfarinupo at least one year with a 60% increase in bone fracture risk due to osteoporosis. Increased risk ofWarfarin steoporosis may be caused by the requirement for vitamin K for the formation of some bone proteins.
The purple tip syndrome is one of the rare side effects of warfarin. The primary symptom is blue or purple color, which most affects the large finger, but can also occur in other parts of the legs. Purple tip syndrome usually occurs until eight weeks after starting warfarin treatment. The probable cause of the purple tip syndrome is the deposit of cholesterol into the skin of the legs.