What Factors Affect Erythrocyte Sedimentation Rate Levels?

Erythrocyte sedimentation rate (erythrocyte sedimentation rate), referred to as ESR. The anticoagulant blood, in the vertical glass tube, its red blood cell sedimentation rate, which indicates the size of red blood cell suspension stability. The faster the erythrocyte sedimentation, the worse the red blood cell suspension stability.

Erythrocyte sedimentation rate

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Erythrocyte sedimentation rate (erythrocyte sedimentation rate), referred to as ESR. The anticoagulant blood, in the vertical glass tube, its red blood cell sedimentation rate, which indicates the size of red blood cell suspension stability. The faster the erythrocyte sedimentation, the worse the red blood cell suspension stability.

Red blood cell suspension stability refers to the characteristic that although the specific gravity of red blood cells is greater than that of plasma, it can remain suspended in plasma and is not easy to sink. When blood flows in the cardiovascular system, red blood cells are difficult to deposit in the plasma. In addition to the fast flow rate and the cells often collide with each other, the red blood cell suspension stability plays an important role. Blood was collected, mixed with anticoagulant, and placed in a container. Although the flow stopped, red blood cells were still suspended in the plasma for a certain period of time. Subsequently, many red blood cells adhered to each other's concave surfaces and overlapped into a string of money. For overlapping. Stack up

The total area of red blood cells in contact with plasma decreases, and the weight per unit area increases, that is, it gradually sinks. The factors that determine the stability of red blood cell suspension are in plasma. The red blood cells of the same individual are suspended in different plasmas, and their sedimentation rates are different. The principle of red blood cell suspension stability may be that the negatively charged sialic glycoproteins on the surface of red blood cells repel the same sex charges. Therefore, red blood cells are not easy to aggregate and maintain suspension stability. If the positively charged proteins (globin, fiber (Protein, etc.) increase, after being adsorbed by red blood cells, the amount of negative charges on its surface is reduced and easy to overlap. The differences in erythrocyte sedimentation rate between normal people are small. Certain diseases change the erythrocyte sedimentation rate, such as rheumatic fever, tuberculosis and other patients. Some diseases cause slowed ESR, such as allergic diseases such as asthma and urticaria. The normal standard of erythrocyte sedimentation rate varies with the inner diameter of the esophageal canal, the height of the thrombus, and the anticoagulant used in various measurement methods.