What Is a Biomarker?

Biomarker refers to biochemical indicators that can mark changes or possible changes in the structure or function of systems, organs, tissues, cells, and subcellular cells, and has a wide range of uses. Biomarkers can be used to diagnose diseases, determine stage of disease, or to evaluate the safety and effectiveness of new drugs or treatments in target populations.

Biomarkers

Right!

Biomarker means that it can mark systems, organs, tissues, cells and

For disease research, biomarkers generally refer to a characteristic biochemical indicator in the ordinary physiological or pathological or therapeutic process that can be objectively measured and evaluated. By measuring it, we can know the biological process that the body is currently in Process. Check for a disease

It is generally divided into functions:

Exposure (exposure) to biomarkers

(Biomarker of exposure);

Effect biomarker

(Biomarker of effect);

Sensitive biomarker

(Susceptibility of biomarker)

1. The selected biomarker must have a certain specificity.

2. The selected biomarker must have sufficient sensitivity, that is, there must be a dose-response relationship between the level of the selected marker and the level of external exposure, and this relationship can be maintained under the level of harmless exposure.

3. Analysis of selected biomarkers

1. Have a certain sensitivity, the sensitivity should be higher than the general biological detection indicators, can be measured at low doses, and can be traced;

2. Reactive

It can clarify the action mechanism of various pollutants, determine the interactions between various pollutants and organisms, and link them with ecological effects, so as to formulate research solutions to environmental problems (such as the decline of population levels, etc.) .