What Is Antibody-Dependent Enhancement?

Antibody dependent enhancement (ADE) After certain virus-specific antibodies (generally non-neutralizing antibodies) are combined with the virus, the virus-bound antibody can pass through its Fc segment to certain cells expressing FcR on its surface. Binding thereby mediates the entry of the virus into these cells, which enhances the viral infectious processes, such as dengue virus.

Antibody-dependent enhancement

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Antibody dependent enhancement (ADE) After certain virus-specific antibodies (generally non-neutralizing antibodies) are combined with the virus, the virus-bound antibody can pass through its Fc segment to certain cells expressing FcR on its surface. Binding thus mediates the entry of the virus into these cells, thereby enhancing the infectious processes of the virus, such as dengue virus.

Of course, after the antibody and virus form a complex, they can also bind to complement and then enter the cell through the complement receptor, which is also a way.