What Is Diffuse Scleroderma?

Diffuse scleroderma is a type of systemic scleroderma. It is more common, showing symmetrical limbs, facial skin tightening, hardening, and thickening, which can affect the proximal extremities, neck, and trunk, as well as visceral damage such as the gastrointestinal tract, kidneys, lungs, and heart. This type is characterized by rapid onset, rapid progress of skin damage, early appearance of visceral damage, and poor prognosis; laboratory tests show positive anti-Scl-70 antibodies, and anti-centromere antibodies can also be positive.

Diffuse scleroderma

Diffuse scleroderma is a type of systemic scleroderma. It is more common, showing symmetrical limbs, facial skin tightening, hardening, and thickening, which can affect the proximal extremities, neck, and trunk, as well as visceral damage such as the gastrointestinal tract, kidneys, lungs, and heart. This type is characterized by rapid onset, rapid progress of skin damage, early appearance of visceral damage, and poor prognosis; laboratory tests show positive anti-Scl-70 antibodies, and anti-centromere antibodies can also be positive.

Complications of diffuse scleroderma

(1) joint damage;

(2) damage to the gastrointestinal smooth muscle;

(3) malnutrition;

(D) formation of fibrous tissue in the heart muscle which may cause permanent damage and / or functional degradation;

(5) kidney damage and / or renal dysfunction;

(6) The thyroid gland forms fibrous tissue.