What is focal segmental glomerulosclerosis?
Focal segmental glomerulosclerosis or FSG is a kidneys affecting. It is a form of glomerulonephritis, a disease in which the glomeruli is damaged. Glomeruli consists of many small units inside each kidney that filter blood as part of the urine formation process. In focal segment glomerulosclerosis, there is scarring inside some glomeruli. This disease is described as focal because it affects only some of the glomeruli and segment, because only the segment or part of each is damaged. What is called primary focal segmental glomerulosclerosis is not unknown. Usually, when people relate to focal segmental glomerulosclerosis, discussed the primary form of the disease.Nkles, fluid retention and increased weight. The presence of protein in the urine could cause foam to appear. Sometimes there are no symptoms, but the protein is detected in the urine during a routine control. When a large amount of protein and excessThe fluid causes the ankles to increase, it is known as nephrotic syndrome, a condition that can be caused by a number of kidney disease.
Complications of focal segment glomerulosclerosis may include high blood pressure or hypertension, which in turn can cause further kidney damage. Cholesterol levels may increase in some people. The kidney function may deteriorate and in more severe cases the kidney failure may occur.
In some people, steroid treatment may be successful and high doses can lead to improvement. Other medicines that affect the immune system such as cyclosporin may be beneficial steroids do not work. It is important to treat symptoms of FSG and therapy may include special diet, reducing salt and drugs that reduce blood pressure, cholesterol and excess fluid. If the kidneys fail, dialysis and renal transplantation may be required.
outlook for people with focalThe segment glomerulosclerosis is variable. Sometimes the disease remains stable for many years and can sometimes disappear alone. If there is a surplus of liquid and swollen ankles, these factors may deteriorate. Within ten years, more than half of the FSGS cases are expected to fail kidney failure.