What is a liquid -based cytology?

liquid -based cytology (LBC) is a method of preparing cervical cells for examination in a laboratory after a paint. Pap paint is a gynecological screening test primarily used to detect cancer cells in the cervix, but can also detect infections and other abnormalities. LBC is a newer way to explore a sample taken from a paint that is expected to be more sensitive and therefore better, but some studies show that an increased number of false positives come with increased sensitivity. The small cell sample is slightly scraped from the cervix, placed on a microscopic slip and sent to the laboratory for dyeing and cytologist analysis. Unlike the traditional parrot, where the cells are located directly on the microscopic glass, the spatula head is separated in the liquid -based cytology and placed in a vial containing conservative liquid. Most liquid preservatives for liquid -based cytology are based on ethanol.

vial is then sent to the laboratory where the liquid isUtina is centrifuged to separate uterine cells from preservatives and other materials collected by spatula. A small sample of cervical cells is collected from the centrifuge and applied to the slides. The image can then be colored and examined in the same way as the traditional pap paint by a cytologist.

Cytology based on liquid has become more common in hospitals and clinics since the 90s. The spinning process makes it possible to analyze brighter and more uniform samples that are easier to analyze for cytologists. This has also helped reduce the number of unreadable or inconclusive tests, which requires that fewer women return to clinics for repeated testing. Liquid samples are also more suitable for testing human papillomavirus (HPV).

Some study suggests that liquid -based cytology increases the sensitivity and specificity of cytological reports, which increases more efficient papers in cancer detection and yin detectionthe diseases. Other studies claim that liquid -based cytology is not more effective than traditional papers. Despite the debate among doctors, cytology based on liquid in many clinical laboratories remains common.