What is Pick's disease?

Pick's disease is a rare neurodegenerative disorder that causes atrophy or gradual wasting away the frontal and time lobes of the brain that are responsible for higher knowledge, processing of speech and vision and long -term memory. It is characterized by the destruction of nerve cells in the brain and accumulation of Tau proteins, a normally occurring protein in the neurons of the central nervous system, to concentrations known as “selection bodies”. Pick's disease is named after the German neurologist and psychiatrist Arnold Pick, who discovered pathology in 1892. It is not known what causes Pick's disease but no genetic foundation was identified.

Pick's disease is one of many pathologies that can cause the frontotemporal Lobar degeneration. There are three different manifestations of frontotemporal degeneration Lobar: frontotemporal dementia, progressive non -functional aphasia and semantic dementia. Semantic dementia is less associated with a pick disease than openty.

Fronotemporal Dementia causesTwo types of symptoms: behavioral symptoms and loss of powerful function. Behavioral symptoms may include personality, apathy and extreme lethargy or inappropriate behavior due to complete disinhibition. The patient may become incapable of basic care or can indulge in risky and socially unacceptable behavior, such as open sexual comments or theft. The loss of a powerful function is characterized by difficulties in performing tasks that include comprehensive planning and often manifest themselves through language damage.

Progressive non -functional aphasia is a type of language damage in which the patient shows difficulty speaking. This deterioration can take many forms. The patient may show apraxia or difficulty in creating speech sounds or can develop stuttering. Other possible forms include anomia, inability to remember names or nouns; Angramatism or inability to mlUvit with normal verbal order and verb times; and phonemic paraffas in which the patient uses incorrect consonants or vowels in his speech. A patient with progressive non -luminous aphasia may show one or many of these symptoms and deteriorate over time over time.

Semantic dementia was first described by Arnold Pick in 1904, but is not caused by a pick disease as often as the other two forms of frontotemporal degeneration of Lobar. Semantic dementia is characterized by the inability of the patient to remember the meanings of words and visual stimuli. A patient suffering from semantic dementia can show anomia and impaired understanding of others' speech. It may also be able to compare semantically related images or can often call things a bad name.