What is the progression of the tumor?

Tumor progression concerns the steps and phases through which a cancer tumor passes as it grows or spreads. The development of a single tumor generally includes three phases: hyperplasia, dysplasia and cancer. The total progression of cancer with malignant tumors can also undergo four or more separate phases, as cancer metastasizes to other areas of the body. The causes of the genetic change of the cell of the original cell are often unknown. During hyperplasia, the cell is uncontrolled and creates excessive suitability of itself. These cells have reached the phase of dysplasia when they begin to succumb to structural changes that give them an unusual and irregular appearance. Once the cells cover a large area contained and succumb to functional changes that cause them unnecessary in their original duties, carcinoma has occurred.

carcinoma in situ is a single tumor. Tumors often appear to be hard, compact mass due to disorganized cell nature. They can occur in almost any cell in the body and therefore tumors are found on whatthe organ of the body. Cancer that occurs in the blood or skin can occupy a different or clearly visible unusual appearance. Any malignant tumor can initiate the metastase process.

Metastases facilitate tumor progression to other previously non -compliance areas of the body. Mutations in two types of genes usually create conditions for tumor progression: oncogens and tumor suppressors. Okogens are substances in the body responsible for cell division and cell movement. Sometimes a change in these genes can cause an exexert effect, which in turn causes rapid cell growth and high protein concentration. At the same time, the mutations can inactivate tumor suppressor genes. These genes are security guards that stopped abnormal cell division; If they are neutralized, then oncogens perform their destructive behavior unchecked.

Cancer progression is often divided into phases that characterize initial support or progressionDR and the degree of metastases. In addition to the above -mentioned cellular makeup cells and expression of spread, other factors that determine the stage of cancer, tumor size, tumor location and a specific role of lymph nodes in cancer. Various staging systems are used, but one known system divides cancer and tumor progression into four phases. More advanced cancer in the third or fourth phase are generally larger tumors and tumor cells that have achieved lymph nodes. Metastases of the surrounding organs have also occurred in the latest cancer at the late stage.