What is amyotrophie?

amyotrophy is a weakness and waste of muscles or limbs. There are many different conditions that are related to amyotrophy, but the most common two are monomely amyotrophy (MMA) and hereditary neuralgic amyotrophy (driving). These two conditions are similar in that they include a waste of muscle or limb, but the driving is usually concentrated on the shoulder and accompanied by severe pain. MMA also usually occurs in the upper limbs, but may also occur in the legs and is not accompanied by pain.

MMA has no clearly defined cause. The condition usually represents in a part of one of the upper limbs of the patient. The muscle will waste away, but this will gradually happen before the stages period, where the condition does not deteriorate unnecessarily. There is a chance that the condition will spread to the limb on the other side of the body, but it usually does not happen. MMA is most common in Asia, especially in Japan and India. The condition usually affects men and is more likely to occur at the age of 15 to 25 years.

The second disease, driving, is known to be a hereditary condition, which means that it is likely only if the patient has a family history. It is known that the SEPT9 gene is associated with driving development, in approximately 85 percent of reported cases. If one of the patient's parents has a condition, he will have a 50 % chance of developing the condition himself. The driving is first manifested by extreme pain in the shoulder or upper part of the arm and after several weeks the affected limb develops amyotrophy. The condition usually develops around 28 years and the patient experiences attacks in the affected limb. These attacks increase the patient's age.

MMA and HNA are conditions for which there is no treatment and treatment is usually aimed at making the patient more masterful. In driving, due to severe pain that is usually associated with the condition, the main goal is to treat pain. MMA treatment focuses more on strengthening the weak limb. Prevention is difficult in both conditions, although prenatalDiagnosis of driving is a possibility. This test is available for all parents who have the risk of transmitting a mutated gene to their child.