What is vascular endothelial growth factor?

Vascular endothelial growth factor, or vegf, is a molecule that contributes to the formation of blood vessels. It stimulates cells for division and changes and is important in the development of blood vessels in embryo, wound repair, muscle formation and circumvention of blood vessel blocks. Sometimes vascular endothelial growth factor is involved in the development of abnormal blood vessels that occur during cancer growth. Abnormal blood vessel growth is associated with a number of diseases, including macular degeneration, where a view may be lost. Understanding factors such as Vegf, and creating drugs that affect their actions can help treat such diseases.

Vegf is what is referred to as an angiogenic growth factor. Angiology is the study of blood vessels and the process that is created by new ones is called angiogenesis, so the angiogenic substance is something that stimulates blood vessels to create. When angiogenesis in conjunction with existing blood vessels, angiogenic growth factors such as Vegf are connected to special receptors on cells that lThey emit blood vessels. They stimulate cells to produce enzymes that dissolve the membrane to which they are fixed and create holes. The cells are then divided and moved through these holes to create a new branch of blood vessels, while various enzymes break down the tissue surrounding it, creating space for its growth.

6 This occurs under conditions such as stroke and heart disease. Too many angiogenic growth factor causes overgrowth of blood vessels that can supply patient tissues while damaging healthy ones. Excessive blood vessel formation is found in diseases including psoriasis, hyperthyroidisp, cancer, diabetic eye diseases and macular degeneration.

Vegf was used to treat macular degeneration, a disease where blood vessels in the eye grow abnormally and eventually destroy the look of a person. The cells in the retina are starving of oxygen, so the vascular endothelial growth factor causes the growth of new blood vessels but those JSOUR FIGHTS AND CENTRAL VISION area will end up scarred and unable to function. Drugs that are injected into the eye have been developed and which stop the vascular endothelial growth factor when connected to receptors on blood vessels to normally stimulate growth.

A number of diseases can be treated using the properties of vascular endothelial growth factor. It can be used directly to increase the production of blood vessels and blood supply to damaged tissues found in wounds or heart disease. Alternatively, drugs can be focused against it, prevents its function and suppresses the growth of blood vessels in disusnate, such as cancer.